PDB entry 1hp7

View 1hp7 on RCSB PDB site
Description: a 2.1 angstrom structure of an uncleaved alpha-1-antitrypsin shows variability of the reactive center and other loops
Class: protein binding
Keywords: uncleaved alpha-1-antitrypsin serpin
Deposited on 2000-12-12, released 2001-03-14
The last revision prior to the SCOP 1.73 freeze date was dated 2003-04-01, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.219
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: alpha-1-antitrypsin
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01009 (Start-393)
      • engineered (69)
      • see remark 999 (100)
      • see remark 999 (375)
    Domains in SCOP 1.73: d1hp7a_
  • Heterogens: ZN, BME, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1hp7A (A:)
edpqgdaaqktdtshhdqdhptfnkitpnlaefafslyrqlahqsnstniffspvsiata
famlslgtkgdthdeileglnfnlteipeaqihegfqellhtlnqpdsqlqlttgnglfl
seglklvdkfledvkklyhseaftvnfgdteeakkqindyvekgtqgkivdlvkeldrdt
vfalvnyiffkgkwerpfevkdteeedfhvdqvttvkvpmmkrlgmfniqhckklsswvl
lmkylgnataifflpdegklqhlenelthdiitkflenedrrsaslhlpklsitgtydlk
svlgqlgitkvfsngadlsgvteeaplklskavhkavltidekgteaagamfleaipmsi
ppevkfnkpfvflmidqntksplfmgkvvnptqk

    Sequence, based on observed residues (ATOM records): (download) 
    >1hp7A (A:)
dhptfnkitpnlaefafslyrqlahqsnstniffspvsiatafamlslgtkgdthdeile
glnfnlteipeaqihegfqellhtlnqpdsqlqlttgnglflseglklvdkfledvkkly
hseaftvnfgdteeakkqindyvekgtqgkivdlvkeldrdtvfalvnyiffkgkwerpf
evkdteeedfhvdqvttvkvpmmkrlgmfniqhckklsswvllmkylgnataifflpdeg
klqhlenelthdiitkflenedrrsaslhlpklsitgtydlksvlgqlgitkvfsngadl
sgvteeaplklskavhkavltidekgteaagamfleaipmsippevkfnkpfvflmidqn
tksplfmgkvvnptqk