PDB entry 1hmv

View 1hmv on RCSB PDB site
Description: the structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1
Class: nucleotidyltransferase
Keywords: nucleotidyltransferase
Deposited on 1994-12-15, released 1995-03-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: 0.254
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hiv-1 reverse transcriptase (subunit p66)
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: HIV-1 POL
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1hmva1, d1hmva2
  • Chain 'B':
    Compound: hiv-1 reverse transcriptase (subunit p51)
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: HIV-1 POL
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1hmvb_
  • Chain 'C':
    Compound: hiv-1 reverse transcriptase (subunit p66)
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: HIV-1 POL
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1hmvc1, d1hmvc2
  • Chain 'D':
    Compound: hiv-1 reverse transcriptase (subunit p51)
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: HIV-1 POL
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1hmvd_
  • Chain 'E':
    Compound: hiv-1 reverse transcriptase (subunit p66)
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: HIV-1 POL
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1hmve1, d1hmve2
  • Chain 'F':
    Compound: hiv-1 reverse transcriptase (subunit p51)
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: HIV-1 POL
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1hmvf_
  • Chain 'G':
    Compound: hiv-1 reverse transcriptase (subunit p66)
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: HIV-1 POL
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1hmvg1, d1hmvg2
  • Chain 'H':
    Compound: hiv-1 reverse transcriptase (subunit p51)
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: HIV-1 POL
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1hmvh_
  • Heterogens: MG

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1hmvA (A:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdivi
yqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
plvklwyqlekepivgaetfyvdgaanretklgkagyvtnkgrqkvvpltnttnqktelq
aiylalqdsglevnivtdsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahk
giggneqvdklvsagirkil

    Sequence, based on observed residues (ATOM records): (download) 
    >1hmvA (A:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faivdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfrkytaft
ipgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqymddlyvgsdleigqh
rtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiq
klvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvy
ydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkitte
siviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgae
tfyvdgaanretklgkagyvtnkgrqkvvpltnttnqktelqaiylalqdsglevnivtd
sqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvdklvsa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1hmvB (B:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdivi
yqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
plvklwyqlekepivgaetf

    Sequence, based on observed residues (ATOM records): (download) 
    >1hmvB (B:)
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
kwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfrkyta
ftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqymddlyv
gsdleigqhrtkieelrqhllrhpdkwtvqpivlpekdswtvndiqklvgklnwasqiyp
gikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkq
gqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklp
iqketwetwwteywqatwipewefvntpplvklwy

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1hmvC (C:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdivi
yqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
plvklwyqlekepivgaetfyvdgaanretklgkagyvtnkgrqkvvpltnttnqktelq
aiylalqdsglevnivtdsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahk
giggneqvdklvsagirkil

    Sequence, based on observed residues (ATOM records): (download) 
    >1hmvC (C:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faivdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfrkytaft
ipgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqymddlyvgsdleigqh
rtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiq
klvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvy
ydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkitte
siviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgae
tfyvdgaanretklgkagyvtnkgrqkvvpltnttnqktelqaiylalqdsglevnivtd
sqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvdklvsa

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1hmvD (D:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdivi
yqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
plvklwyqlekepivgaetf

    Sequence, based on observed residues (ATOM records): (download) 
    >1hmvD (D:)
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
kwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfrkyta
ftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqymddlyv
gsdleigqhrtkieelrqhllrhpdkwtvqpivlpekdswtvndiqklvgklnwasqiyp
gikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkq
gqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklp
iqketwetwwteywqatwipewefvntpplvklwy

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1hmvE (E:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdivi
yqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
plvklwyqlekepivgaetfyvdgaanretklgkagyvtnkgrqkvvpltnttnqktelq
aiylalqdsglevnivtdsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahk
giggneqvdklvsagirkil

    Sequence, based on observed residues (ATOM records): (download) 
    >1hmvE (E:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faivdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfrkytaft
ipgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqymddlyvgsdleigqh
rtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiq
klvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvy
ydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkitte
siviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgae
tfyvdgaanretklgkagyvtnkgrqkvvpltnttnqktelqaiylalqdsglevnivtd
sqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvdklvsa

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1hmvF (F:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdivi
yqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
plvklwyqlekepivgaetf

    Sequence, based on observed residues (ATOM records): (download) 
    >1hmvF (F:)
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
kwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfrkyta
ftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqymddlyv
gsdleigqhrtkieelrqhllrhpdkwtvqpivlpekdswtvndiqklvgklnwasqiyp
gikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkq
gqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklp
iqketwetwwteywqatwipewefvntpplvklwy

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >1hmvG (G:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdivi
yqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
plvklwyqlekepivgaetfyvdgaanretklgkagyvtnkgrqkvvpltnttnqktelq
aiylalqdsglevnivtdsqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahk
giggneqvdklvsagirkil

    Sequence, based on observed residues (ATOM records): (download) 
    >1hmvG (G:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faivdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfrkytaft
ipgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqymddlyvgsdleigqh
rtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiq
klvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvy
ydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkitte
siviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlekepivgae
tfyvdgaanretklgkagyvtnkgrqkvvpltnttnqktelqaiylalqdsglevnivtd
sqyalgiiqaqpdkseselvnqiieqlikkekvylawvpahkgiggneqvdklvsa

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >1hmvH (H:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpl
dedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdivi
yqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrga
htndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntp
plvklwyqlekepivgaetf

    Sequence, based on observed residues (ATOM records): (download) 
    >1hmvH (H:)
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
kwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfrkyta
ftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqymddlyv
gsdleigqhrtkieelrqhllrhpdkwtvqpivlpekdswtvndiqklvgklnwasqiyp
gikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqkq
gqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfklp
iqketwetwwteywqatwipewefvntpplvklwy