PDB entry 1hh4

View 1hh4 on RCSB PDB site
Description: rac1-rhogdi complex involved in nadph oxidase activation
Class: signaling protein/inhibitor
Keywords: signaling protein/inhibitor, singal protein inhibitor complex, small g protein, gtpase activation, GTP-binding, prenylation, lipoprotein
Deposited on 2000-12-20, released 2001-08-28
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.256
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ras-related c3 botulinum toxin substrate 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15154 (0-End)
      • cloning artifact (77)
      • cloning artifact (0)
    Domains in SCOPe 2.05: d1hh4a_
  • Chain 'B':
    Compound: ras-related c3 botulinum toxin substrate 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15154 (0-End)
      • cloning artifact (77)
      • cloning artifact (0)
    Domains in SCOPe 2.05: d1hh4b_
  • Chain 'D':
    Compound: rho GDP-dissociation inhibitor 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1hh4d_
  • Chain 'E':
    Compound: rho GDP-dissociation inhibitor 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1hh4e_
  • Heterogens: GDP, MG, GER, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1hh4A (A:)
pqaikcvvvgdgavgktcllisyttnafpgeyiptvfdnysanvmvdgkpvnlglwdtag
qedydrlrplsypqtdvslicfslvspasfenvrakwypevrhhcpntpiilvgtkldlr
ddkdtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairavlcpp
pvkkrkrkclll

    Sequence, based on observed residues (ATOM records): (download) 
    >1hh4A (A:)
pqaikcvvvgdgavgktcllisyttnafpgeyiptvfdnysanvmvdgkpvnlglwdtag
qedydrlrplsypqtdvslicfslvspasfenvrakwypevrhhcpntpiilvgtkldlr
ddkdtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairavlcpp
pvkkrkrkc

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1hh4B (B:)
pqaikcvvvgdgavgktcllisyttnafpgeyiptvfdnysanvmvdgkpvnlglwdtag
qedydrlrplsypqtdvslicfslvspasfenvrakwypevrhhcpntpiilvgtkldlr
ddkdtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairavlcpp
pvkkrkrkclll

    Sequence, based on observed residues (ATOM records): (download) 
    >1hh4B (B:)
pqaikcvvvgdgavgktcllisyttnafpgeyiptvfdnysanvmvdgkpvnlglwdtag
qedydrlrplsypqtdvslicfslvspasfenvrakwypevrhhcpntpiilvgtkldlr
ddkdtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairavlcpp
pvkkrkrkc

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1hh4D (D:)
maeqeptaeqlaqiaaeneedehsvnykppaqksiqeiqeldkddeslrkykeallgrva
vsadpnvpnvvvtgltlvcssapgpleldltgdlesfkkqsfvlkegveyrikisfrvnr
eivsgmkyiqhtyrkgvkidktdymvgsygpraeeyefltpveeapkgmlargsysiksr
ftdddktdhlswewnltikkdwkd

    Sequence, based on observed residues (ATOM records): (download) 
    >1hh4D (D:)
eqlaqiaaeneedehsvnykppaqksiqeiqeldkddeslrkykeallgrnvpnvvvtgl
tlvcssapgpleldltgdlesfkkqsfvlkegveyrikisfrvnreivsgmkyiqhtyrk
gvkidktdymvgsygpraeeyefltpveeapkgmlargsysiksrftdddktdhlswewn
ltikkd

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1hh4E (E:)
maeqeptaeqlaqiaaeneedehsvnykppaqksiqeiqeldkddeslrkykeallgrva
vsadpnvpnvvvtgltlvcssapgpleldltgdlesfkkqsfvlkegveyrikisfrvnr
eivsgmkyiqhtyrkgvkidktdymvgsygpraeeyefltpveeapkgmlargsysiksr
ftdddktdhlswewnltikkdwkd

    Sequence, based on observed residues (ATOM records): (download) 
    >1hh4E (E:)
hsvnykppaqksiqeiqeldkddeslrkykeallgrvavsadpnvpnvvvtgltlvcssa
pgpleldltgdlesfkkqsfvlkegveyrikisfrvnreivsgmkyiqhtyrkgvkidkt
dymvgsygpraeeyefltpveeapkgmlargsysiksrftdddktdhlswewnltikkdw