PDB entry 1hdt

View 1hdt on RCSB PDB site
Description: structure of a retro-binding peptide inhibitor complexed with human alpha-thrombin
Class: hydrolase/hydrolase inhibitor
Keywords: SERINE PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 1994-07-25, released 1995-10-15
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.204
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'H':
  Compound: alpha-thrombin
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00734 (0-258)
  Domains in SCOPe 2.03: d1hdt.1
• Chain 'L':
  Compound: alpha-thrombin
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00734 (5-32)
  Domains in SCOPe 2.03: d1hdt.1
• Chain 'P':
  Compound: hirugen peptide
  Species: Hirudo medicinalis [TaxId:6421]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P28507 (Start-11)
• Heterogens: 0E7, HOH

PDB Chain Sequences:

• Chain 'H':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1hdtH (H:)
  ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
  vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
  pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
  itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
  thvfrlkkwiqkvidqfge
  

  
  
• Chain 'L':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1hdtL (L:)
  sgeadcglrplfekksledkterellesyidgr
  

  
  
• Chain 'P':
  No sequence available.