PDB entry 1hak

View 1hak on RCSB PDB site
Description: crystal structure of recombinant human placental annexin v complexed with k-201 as a calcium channel activity inhibitor
Class: calcium/phospholipid-binding
Keywords: annexin v, lipocortin v, endonexin II, placenta anticoagulant protein-I, 35kda calelectrin, inhibitor of blood coagulation, calcium/phospholipid-binding
Deposited on 1997-12-10, released 1999-02-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.206
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: annexin v
    Species: Homo sapiens [TaxId:9606]
    Gene: CDNA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1haka_
  • Chain 'B':
    Compound: annexin v
    Species: Homo sapiens [TaxId:9606]
    Gene: CDNA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1hakb_
  • Heterogens: K21, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1hakA (A:)
maqvlrgtvtdfpgfderadaetlrkamkglgtdeesiltlltsrsnaqrqeisaafktl
fgrdllddlkseltgkfeklivalmkpsrlydayelkhalkgagtnekvlteiiasrtpe
elraikqvyeeeygssleddvvgdtsgyyqrmlvvllqanrdpdagideaqveqdaqalf
qagelkwgtdeekfitifgtrsvshlrkvfdkymtisgfqieetidretsgnleqlllav
vksirsipaylaetlyyamkgagtddhtlirvmvsrseidlfnirkefrknfatslysmi
kgdtsgdykkallllcgedd

    Sequence, based on observed residues (ATOM records): (download) 
    >1hakA (A:)
qvlrgtvtdfpgfderadaetlrkamkglgtdeesiltlltsrsnaqrqeisaafktlfg
rdllddlkseltgkfeklivalmkpsrlydayelkhalkgagtnekvlteiiasrtpeel
raikqvyeeeygssleddvvgdtsgyyqrmlvvllqanrdpdagideaqveqdaqalfqa
gelkwgtdeekfitifgtrsvshlrkvfdkymtisgfqieetidretsgnleqlllavvk
sirsipaylaetlyyamkgagtddhtlirvmvsrseidlfnirkefrknfatslysmikg
dtsgdykkallllcgedd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1hakB (B:)
maqvlrgtvtdfpgfderadaetlrkamkglgtdeesiltlltsrsnaqrqeisaafktl
fgrdllddlkseltgkfeklivalmkpsrlydayelkhalkgagtnekvlteiiasrtpe
elraikqvyeeeygssleddvvgdtsgyyqrmlvvllqanrdpdagideaqveqdaqalf
qagelkwgtdeekfitifgtrsvshlrkvfdkymtisgfqieetidretsgnleqlllav
vksirsipaylaetlyyamkgagtddhtlirvmvsrseidlfnirkefrknfatslysmi
kgdtsgdykkallllcgedd

    Sequence, based on observed residues (ATOM records): (download) 
    >1hakB (B:)
qvlrgtvtdfpgfderadaetlrkamkglgtdeesiltlltsrsnaqrqeisaafktlfg
rdllddlkseltgkfeklivalmkpsrlydayelkhalkgagtnekvlteiiasrtpeel
raikqvyeeeygssleddvvgdtsgyyqrmlvvllqanrdpdagideaqveqdaqalfqa
gelkwgtdeekfitifgtrsvshlrkvfdkymtisgfqieetidretsgnleqlllavvk
sirsipaylaetlyyamkgagtddhtlirvmvsrseidlfnirkefrknfatslysmikg
dtsgdykkallllcgedd