PDB entry 1hah

View 1hah on RCSB PDB site
Description: the isomorphous structures of prethrombin2, hirugen-and ppack-thrombin: changes accompanying activation and exosite binding to thrombin
Class: complex(serine proteinase/inhibitor)
Keywords: COMPLEX(SERINE PROTEINASE-INHIBITOR), COMPLEX(SERINE PROTEINASE-INHIBITOR) complex
Deposited on 1994-06-27, released 1994-12-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-29, with a file datestamp of 2017-11-24.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: alpha-thrombin (large subunit)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1hah.1
  • Chain 'I':
    Compound: hirugen
    Species: Hirudo medicinalis [TaxId:6421]
    Database cross-references and differences (RAF-indexed):
    • PDB 1HAH (0-9)
  • Chain 'L':
    Compound: alpha-thrombin (small subunit)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1hah.1
  • Heterogens: NAG, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >1hahH (H:)
    ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
    vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
    pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
    itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
    thvfrlkkwiqkvidqfge
    

    Sequence, based on observed residues (ATOM records): (download)
    >1hahH (H:)
    ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
    vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
    pdretaasllqagykgrvtgwgnlketwgqpsvlqvvnlpiverpvckdstriritdnmf
    cagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrl
    kkwiqkvidqfge
    

  • Chain 'I':
    No sequence available.

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1hahL (L:)
    tfgsgeadcglrplfekksledkterellesyidgr