PDB entry 1h78

View 1h78 on RCSB PDB site
Description: structural basis for allosteric substrate specificity regulation in class III ribonucleotide reductases: nrdd in complex with dctp.
Class: oxidoreductase
Keywords: oxidoreductase, reductase, allosteric regulation, substrate specificity
Deposited on 2001-07-04, released 2002-07-04
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.221
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: anaerobic ribonucleotide-triphosphate reductase large chain
    Species: BACTERIOPHAGE T4 [TaxId:10665]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9T0V5
      • engineered mutation (579)
    Domains in SCOPe 2.02: d1h78a_
  • Heterogens: DCP, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1h78A (A:)
mtiekeieglihktnkdllnenankdsrvfptqrdlmagivskhiaknmvpsfimkahes
giihvhdidyspalpftncclvdlkgmlengfklgnaqietpksigvataimaqitaqva
shqyggttfanvdkvlspyvkrtyakhiedaekwqiadalnyaqsktekdvydafqayey
evntlfssngqtpfvtitfgtgtdwtermiqkailknrikglgrdgitpifpklvmfvee
gvnlykddpnydikqlalecaskrmypdiisaknnkaitgssvpvspmgcrsflsvwkds
tgneildgrnnlgvvtlnlprialdsyigtqfneqkfvelfnermdlcfealmcrisslk
gvkatvapilyqegafgvrlkpdddiielfkngrssvslgyigihelnilvgrdigreil
tkmnahlkqwtertgfafslystpaenlcyrfckldtekygsvkdvtdkgwytnsfhvsv
eenitpfekisreapyhfiatgghisyvelpdmknnlkgleavwdyaaqhldyfgvnmpv
dkcftcgsthemtptengfvcsicgetdpkkmntirrtcaylgnpnergfnlgknkeimh
rvkhq

    Sequence, based on observed residues (ATOM records): (download) 
    >1h78A (A:)
dsrvfptqrdlmagivskhiaknmvpsfimkahesgiihvhdidyspalpftncclvdlk
gmlengfklgnaqietpksigvataimaqitaqvashqyggttfanvdkvlspyvkrtya
khiedaekwqiadalnyaqsktekdvydafqayeyevntlfssntpfvtitfgtgtdwte
rmiqkailknrikglgrdgitpifpklvmfveegvnlykddpnydikqlalecaskrmyp
diisaknnkaitgssvpvspmgcrsflsvwkdstgneildgrnnlgvvtlnlprialdsy
igtqfneqkfvelfnermdlcfealmcrisslkgvkatvapilyqegafgvrlkpdddii
elfkngrssvslgyigihelnilvgrdigreiltkmnahlkqwtertgfafslystpaen
lcyrfckldtekygsvkdvtdkgwytnsfhvsveenitpfekisreapyhfiatgghisy
velpdmknnlkgleavwdyaaqhldyfgvnmpvdkcftmntirrtcaylgnpne