PDB entry 1h5s

View 1h5s on RCSB PDB site
Description: thymidylyltransferase complexed with tmp
Class: transferase
Keywords: transferase, pyrophosphatase, nucleotide sugar methabolism
Deposited on 2001-05-25, released 2001-11-23
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.176
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glucose-1-phosphate thymidylyltransferase
    Species: Escherichia coli, synthetic [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P37744
      • conflict (184)
      • conflict (216)
      • conflict (287)
      • conflict (101)
    Domains in SCOPe 2.05: d1h5sa_
  • Chain 'B':
    Compound: glucose-1-phosphate thymidylyltransferase
    Species: Escherichia coli, synthetic [TaxId:562]
    Domains in SCOPe 2.05: d1h5sb_
  • Chain 'C':
    Compound: glucose-1-phosphate thymidylyltransferase
    Species: Escherichia coli, synthetic [TaxId:562]
    Domains in SCOPe 2.05: d1h5sc_
  • Chain 'D':
    Compound: glucose-1-phosphate thymidylyltransferase
    Species: Escherichia coli, synthetic [TaxId:562]
    Domains in SCOPe 2.05: d1h5sd_
  • Heterogens: TMP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1h5sA (A:)
mkmrkgiilaggsgtrlypvtmavskqllpiydkpmiyyplstlmlagirdiliistpqd
tprfqqllgdgsqwglnlqykvqpspdglaqafiigeefiggddcalvlgdnifyghdlp
klmeaavnkesgatvfayhvndperygvvefdkngtaisleekplepksnyavtglyfyd
ndvvlmaknlkpsargeleitdinriyleqgrlsvalmgrgyawldtgthqslieasnfi
atieerqglkvscpeeiafrkgfidveqvrklavpliknnygqylykmtkdsn

    Sequence, based on observed residues (ATOM records): (download) 
    >1h5sA (A:)
kmrkgiilaggsgtrlypvtmavskqllpiydkpmiyyplstlmlagirdiliistpqdt
prfqqllgdgsqwglnlqykvqpspdglaqafiigeefiggddcalvlgdnifyghdlpk
lmeaavnkesgatvfayhvndperygvvefdkngtaisleekplepksnyavtglyfydn
dvvlmaknlkpsargeleitdinriyleqgrlsvalmgrgyawldtgthqslieasnfia
tieerqglkvscpeeiafrkgfidveqvrklavpliknnygqylykmtkd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1h5sB (B:)
mkmrkgiilaggsgtrlypvtmavskqllpiydkpmiyyplstlmlagirdiliistpqd
tprfqqllgdgsqwglnlqykvqpspdglaqafiigeefiggddcalvlgdnifyghdlp
klmeaavnkesgatvfayhvndperygvvefdkngtaisleekplepksnyavtglyfyd
ndvvqmaknlkpsargeleitdinriyleqgrlsvalmgrgyawldtgthqslieasnfi
atieerqglkvscpeeiafrkgfidveqvrklavpliknnygqylykqtkdsn

    Sequence, based on observed residues (ATOM records): (download) 
    >1h5sB (B:)
mkmrkgiilaggsgtrlypvtmavskqllpiydkpmiyyplstlmlagirdiliistpqd
tprfqqllgdgsqwglnlqykvqpspdglaqafiigeefiggddcalvlgdnifyghdlp
klmeaavnkesgatvfayhvndperygvvefdkngtaisleekplepksnyavtglyfyd
ndvvqmaknlkpsargeleitdinriyleqgrlsvalmgrgyawldtgthqslieasnfi
atieerqglkvscpeeiafrkgfidveqvrklavpliknnygqylykqtkd

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1h5sC (C:)
mkmrkgiilaggsgtrlypvtmavskqllpiydkpmiyyplstlmlagirdiliistpqd
tprfqqllgdgsqwglnlqykvqpspdglaqafiigeefiggddcalvlgdnifyghdlp
klmeaavnkesgatvfayhvndperygvvefdkngtaisleekplepksnyavtglyfyd
ndvvqmaknlkpsargeleitdinriyleqgrlsvammgrgyawldtgthqslieasnfi
atieerqglkvscpeeiafrkgfidveqvrklavpliknnygqylykmtkdsn

    Sequence, based on observed residues (ATOM records): (download) 
    >1h5sC (C:)
kmrkgiilaggsgtrlypvtmavskqllpiydkpmiyyplstlmlagirdiliistpqdt
prfqqllgdgsqwglnlqykvqpspdglaqafiigeefiggddcalvlgdnifyghdlpk
lmeaavnkesgatvfayhvndperygvvefdkngtaisleekplepksnyavtglyfydn
dvvqmaknlkpsargeleitdinriyleqgrlsvammgrgyawldtgthqslieasnfia
tieerqglkvscpeeiafrkgfidveqvrklavpliknnygqylykmtkd

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1h5sD (D:)
mkmrkgiilaggsgtrlypvtmavskqllpiydkpmiyyplstlmlagirdiliistpqd
tprfqqllgdgsqwglnlqykvqpspdglaqafiigeefigaddcalvlgdnifyghdlp
klmeaavnkesgatvfayhvndperygvvefdkngtaisleekplepksnyavtglyfyd
ndvvqmaknlkpsargeleitdinriyleqgrlsvalmgrgyawldtgthqslieasnfi
atieerqglkvscpeeiafrkgfidveqvrklavpliknnygqylykmtkdsn

    Sequence, based on observed residues (ATOM records): (download) 
    >1h5sD (D:)
kmrkgiilaggsgtrlypvtmavskqllpiydkpmiyyplstlmlagirdiliistpqdt
prfqqllgdgsqwglnlqykvqpspdglaqafiigeefigaddcalvlgdnifyghdlpk
lmeaavnkesgatvfayhvndperygvvefdkngtaisleekplepksnyavtglyfydn
dvvqmaknlkpsargeleitdinriyleqgrlsvalmgrgyawldtgthqslieasnfia
tieerqglkvscpeeiafrkgfidveqvrklavpliknnygqylykmtkd