PDB entry 1h4l

View 1h4l on RCSB PDB site
Description: structure and regulation of the cdk5-p25(nck5a) complex
Class: complex(cyclins/cdk)
Keywords: cyclins, cyclin-dependent kinases, cdk5, p35, p25, transferase, ATP-binding, cell cycle, cell division, phosphorylation
Deposited on 2001-05-11, released 2002-08-14
The last revision prior to the SCOP 1.73 freeze date was dated 2003-04-01, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: 0.236
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cell division protein kinase 5
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q00535
      • conflict (198)
    Domains in SCOP 1.73: d1h4la_
  • Chain 'B':
    Compound: cell division protein kinase 5
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q00535
      • conflict (198)
    Domains in SCOP 1.73: d1h4lb_
  • Chain 'D':
    Compound: cyclin-dependent kinase 5 activator
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1h4ld_
  • Chain 'E':
    Compound: cyclin-dependent kinase 5 activator
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1h4le_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1h4lA (A:)
mqkyeklekigegtygtvfkaknretheivalkrvrlddddegvpssalreicllkelkh
knivrlhdvlhsdkkltlvfefcdqdlkkyfdscngdldpeivksflfqllkglgfchsr
nvlhrdlkpqnllinrngelkladfglarafgipvrcysaevvtlwyrppdvlfgaklys
tsidmwsagcifaelanaarplfpgndvddqlkrifrllgtpteeqwpsmtklpdykpyp
mypattslvnvvpklnatgrdllqnllkcnpvqrisaeealqhpyfsdfcpp

    Sequence, based on observed residues (ATOM records): (download) 
    >1h4lA (A:)
qkyeklekiygtvfkaknretheivalkrvrldgvpssalreicllkelkhknivrlhdv
lhsdkkltlvfefcdqdlkkyfdscngdldpeivksflfqllkglgfchsrnvlhrdlkp
qnllinrngelkladfglarafgipvrcysaevvtlwyrppdvlfgaklystsidmwsag
cifaelanaarplfpgndvddqlkrifrllgtpteeqwpsmtklpdykpypmypattslv
nvvpklnatgrdllqnllkcnpvqrisaeealqhpyfs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1h4lB (B:)
mqkyeklekigegtygtvfkaknretheivalkrvrlddddegvpssalreicllkelkh
knivrlhdvlhsdkkltlvfefcdqdlkkyfdscngdldpeivksflfqllkglgfchsr
nvlhrdlkpqnllinrngelkladfglarafgipvrcysaevvtlwyrppdvlfgaklys
tsidmwsagcifaelanaarplfpgndvddqlkrifrllgtpteeqwpsmtklpdykpyp
mypattslvnvvpklnatgrdllqnllkcnpvqrisaeealqhpyfsdfcpp

    Sequence, based on observed residues (ATOM records): (download) 
    >1h4lB (B:)
qkyeklekiygtvfkaknretheivalkrvrldgvpssalreicllkelkhknivrlhdv
lhsdkkltlvfefcdqdlkkyfdscngdldpeivksflfqllkglgfchsrnvlhrdlkp
qnllinrngelkladfglarafgipvrcysaevvtlwyrppdvlfgaklystsidmwsag
cifaelanaarplfpgndvddqlkrifrllgtpteeqwpsmtklpdykpypmypattslv
nvvpklnatgrdllqnllkcnpvqrisaeealqhpyfs

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1h4lD (D:)
stsellrclgeflcrrcyrlkhlsptdpvlwlrsvdrslllqgwqdqgfitpanvvflym
lcrdvissevgsdhelqavlltclylsysymgneisyplkpflvesckeafwdrclsvin
lmsskmlqinadphyftqvfsdlknes

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1h4lE (E:)
stsellrclgeflcrrcyrlkhlsptdpvlwlrsvdrslllqgwqdqgfitpanvvflym
lcrdvissevgsdhelqavlltclylsysymgneisyplkpflvesckeafwdrclsvin
lmsskmlqinadphyftqvfsdlknes