PDB entry 1h2k
View 1h2k on RCSB PDB site
Description: Factor Inhibiting HIF-1 alpha in complex with HIF-1 alpha fragment peptide
Class: transcription activator/inhibitor
Keywords: transcription activator-inhibitor complex, fih, hif, dsbh, oxygenase, transcription, hypoxia, 2- oxoglutarate, asparaginyl hydroxylase, phosphorylation
Deposited on
2002-08-12, released
2002-11-28
The last revision prior to the SCOPe 2.08 freeze date was dated
2018-02-21, with a file datestamp of
2018-02-16.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: N/A
AEROSPACI score: 0.28
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: factor inhibiting hif1
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1h2ka_ - Chain 'S':
Compound: Hypoxia-inducible factor 1 alpha
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1h2ks_ - Heterogens: FE2, OGA, SO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1h2kA (A:)
maataaeavasgsgepreeagalgpawdesqlrsysfptrpiprlsqsdpraeelienee
pvvltdtnlvypalkwdleylqenigngdfsvysasthkflyydekkmanfqnfkprsnr
eemkfhefveklqdiqqrggeerlylqqtlndtvgrkivmdflgfnwnwinkqqgkrgwg
qltsnllligmegnvtpahydeqqnffaqikgykrcilfppdqfeclypypvhhpcdrqs
qvdfdnpdyerfpnfqnvvgyetvvgpgdvlyipmywwhhiesllnggititvnfwykga
ptpkrieyplkahqkvaimrniekmlgealgnpqevgpllntmikgryn
Sequence, based on observed residues (ATOM records): (download)
>1h2kA (A:)
epreeagalgpawdesqlrsysfptrpiprlsqsdpraeelieneepvvltdtnlvypal
kwdleylqenigngdfsvysasthkflyydekkmanfqnfkprsnreemkfhefveklqd
iqqrggeerlylqqtlndtvgrkivmdflgfnwnwinkqqgkrgwgqltsnllligmegn
vtpahydeqqnffaqikgykrcilfppdqfeclypypvhhpcdrqsqvdfdnpdyerfpn
fqnvvgyetvvgpgdvlyipmywwhhiesllnggititvnfwykgaptpeyplkahqkva
imrniekmlgealgnpqevgpllntmikgryn
- Chain 'S':
Sequence, based on SEQRES records: (download)
>1h2kS (S:)
smdesglpqltsydcevnapiqgsrnllqgeellraldqvn
Sequence, based on observed residues (ATOM records): (download)
>1h2kS (S:)
ltsydcevnapillqgeellrald