PDB entry 1h1w

View 1h1w on RCSB PDB site
Description: high resolution crystal structure of the human pdk1 catalytic domain
Class: transferase
Keywords: phosphoinositide dependent protein kinase, pka, agc kinase activation, pif-pocket, pi3-kinase signalling, transferase, serine/threonine-protein kinase, ATP-binding
Deposited on 2002-07-23, released 2003-07-17
The last revision prior to the SCOP 1.73 freeze date was dated 2003-07-17, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.196
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-phosphoinositide dependent protein kinase-1
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1h1wa_
  • Heterogens: SO4, ATP, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1h1wA (A:)
ppqprkkrpedfkfgkilgegsfstvvlarelatsreyaikilekrhiikenkvpyvtre
rdvmsrldhpffvklyftfqddeklyfglsyakngellkyirkigsfdetctrfytaeiv
saleylhgkgiihrdlkpenillnedmhiqitdfgtakvlspeskqaransfvgtaqyvs
pellteksackssdlwalgciiyqlvaglppfragneylifqkiikleydfpekffpkar
dlvekllvldatkrlgceemegygplkahpffesvtwenlhqqtppklt

    Sequence, based on observed residues (ATOM records): (download) 
    >1h1wA (A:)
ppqprkkrpedfkfgkilgegsfstvvlarelatsreyaikilekrhiikenkvpyvtre
rdvmsrldhpffvklyftfqddeklyfglsyakngellkyirkigsfdetctrfytaeiv
saleylhgkgiihrdlkpenillnedmhiqitdfgtakvlsparansfvgtaqyvspell
teksackssdlwalgciiyqlvaglppfragneylifqkiikleydfpekffpkardlve
kllvldatkrlgceemegygplkahpffesvtwenlhqqtppklt