PDB entry 1h0w

View 1h0w on RCSB PDB site
Description: human cyclin dependent protein kinase 2 in complex with the inhibitor 2-amino-6-[cyclohex-3-enyl]methoxypurine
Class: transferase
Keywords: transferase, protein kinase, cell cycle, phosphorylation, cell division, mitosis, inhibition
Deposited on 2002-06-27, released 2003-06-27
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.214
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1h0wa_
  • Heterogens: 207, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1h0wA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >1h0wA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirvpstaireisllkelnhpnivkll
    dvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrd
    lkpqnllintegaikladfglarafgvpvtlwyrapeillgckyystavdiwslgcifae
    mvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppl
    dedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl