PDB entry 1h06
View 1h06 on RCSB PDB site
Description: cdk2 in complex with a disubstituted 4, 6-bis anilino pyrimidine cdk4 inhibitor
Class: transferase
Keywords: serine/threonine-protein kinase,mitosis,transferase
Deposited on
2002-06-11, released
2003-07-11
The last revision prior to the SCOPe 2.06 freeze date was dated
2004-05-04, with a file datestamp of
2007-04-25.
Experiment type: XRAY
Resolution: 2.31 Å
R-factor: 0.223
AEROSPACI score: 0.33
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Cell division protein kinase 2
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
- PDB 1H06
- Uniprot P24941 (0-297)
Domains in SCOPe 2.06: d1h06a_ - Heterogens: 3FP, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1h06A (A:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
Sequence, based on observed residues (ATOM records): (download)
>1h06A (A:)
menfqkvekigegtygvvykarnkltgevvalkkirltaireisllkelnhpnivklldv
ihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdlk
pqnllintegaikladfglarvvtlwyrapeillgckyystavdiwslgcifaemvtrra
lfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgrs
llsqmlhydpnkrisakaalahpffqdvtkpvphlrl