PDB entry 1gzg

View 1gzg on RCSB PDB site
Description: complex of a mg2-dependent porphobilinogen synthase from pseudomonas aeruginosa (mutant d139n) with 5-fluorolevulinic acid
Class: lyase
Keywords: lyase, heme biosynthesis, 5-fluorolevulinic acid
Deposited on 2002-05-21, released 2002-06-27
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.66 Å
R-factor: 0.175
AEROSPACI score: 0.57 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: delta-aminolevulinic acid dehydratase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q59643
      • engineered mutation (138)
      • see remark 999 (198)
    Domains in SCOPe 2.06: d1gzga_
  • Chain 'B':
    Compound: delta-aminolevulinic acid dehydratase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q59643
      • engineered mutation (138)
      • see remark 999 (198)
    Domains in SCOPe 2.06: d1gzgb_
  • Heterogens: LAF, MG, NA, SO4, K, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1gzgA (A:)
    msftpanraypytrlrrnrrddfsrrlvrenvltvddlilpvfvldgvnqresipsmpgv
    erlsidqllieaeewvalgipalalfpvtpvekksldaaeaynpegiaqratralrerfp
    elgiitdvaldpftthgqngildddgyvlndvsidvlvrqalshaeagaqvvapsdmmdg
    rigairealesaghtnvrvmaysakyasayygpfrdavgsasnlgkgnkatyqmdpansd
    ealhevaadlaegadmvmvkpgmpyldivrrvkdefraptfvyqvsgeyamhmgaiqngw
    laesvilesltafkragadgiltyfakqaaeqlrrgr
    

    Sequence, based on observed residues (ATOM records): (download)
    >1gzgA (A:)
    nraypytrlrrnrrddfsrrlvrenvltvddlilpvfvldgvnqresipsmpgverlsid
    qllieaeewvalgipalalfpvtpvekksldaaeaynpegiaqratralrerfpelgiit
    dvaldpftthgqngildddgyvlndvsidvlvrqalshaeagaqvvapsdmmdgrigair
    ealesaghtnvrvmaysakyasayygpfrdavgsasnlgkgnkatyqmdpansdealhev
    aadlaegadmvmvkpgmpyldivrrvkdefraptfvyqvsgeyamhmgaiqngwlaesvi
    lesltafkragadgiltyfakqaaeqlrr
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1gzgB (B:)
    msftpanraypytrlrrnrrddfsrrlvrenvltvddlilpvfvldgvnqresipsmpgv
    erlsidqllieaeewvalgipalalfpvtpvekksldaaeaynpegiaqratralrerfp
    elgiitdvaldpftthgqngildddgyvlndvsidvlvrqalshaeagaqvvapsdmmdg
    rigairealesaghtnvrvmaysakyasayygpfrdavgsasnlgkgnkatyqmdpansd
    ealhevaadlaegadmvmvkpgmpyldivrrvkdefraptfvyqvsgeyamhmgaiqngw
    laesvilesltafkragadgiltyfakqaaeqlrrgr
    

    Sequence, based on observed residues (ATOM records): (download)
    >1gzgB (B:)
    panraypytrlrrnrrddfsrrlvrenvltvddlilpvfvldgvnqresipsmpgverls
    idqllieaeewvalgipalalfpvtpvekksldaaeaynpegiaqratralrerfpelgi
    itdvaldpftthgqngildddgyvlndvsidvlvrqalshaeagaqvvapsdmmdgriga
    irealesaghtnvrvmaysakyasayygpfrdavgskatyqmdpansdealhevaadlae
    gadmvmvkpgmpyldivrrvkdefraptfvyqvsgeyamhmgaiqngwlaesvileslta
    fkragadgiltyfakqaaeqlrr