PDB entry 1gxs

View 1gxs on RCSB PDB site
Description: crystal structure of hydroxynitrile lyase from sorghum bicolor in complex with inhibitor benzoic acid: a novel cyanogenic enzyme
Class: lyase
Keywords: lyase, inhibitor complex, cyanogenesis mechanism
Deposited on 2002-04-11, released 2002-10-01
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-10-26, with a file datestamp of 2011-10-21.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.165
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: p-(s)-hydroxymandelonitrile lyase chain a
    Species: SORGHUM BICOLOR [TaxId:4558]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8W4X3 (Start-269)
      • variant (10)
      • variant (78)
      • variant (111)
      • variant (202)
    Domains in SCOPe 2.07: d1gxs.1
  • Chain 'B':
    Compound: p-(s)-hydroxymandelonitrile lyase chain b
    Species: SORGHUM BICOLOR [TaxId:4558]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8W4X3 (0-157)
      • variant (125-127)
    Domains in SCOPe 2.07: d1gxs.1
  • Chain 'C':
    Compound: p-(s)-hydroxymandelonitrile lyase chain a
    Species: SORGHUM BICOLOR [TaxId:4558]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8W4X3 (Start-269)
      • variant (10)
      • variant (78)
      • variant (111)
      • variant (202)
    Domains in SCOPe 2.07: d1gxs.2
  • Chain 'D':
    Compound: p-(s)-hydroxymandelonitrile lyase chain b
    Species: SORGHUM BICOLOR [TaxId:4558]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8W4X3 (0-157)
      • variant (125-127)
    Domains in SCOPe 2.07: d1gxs.2
  • Heterogens: BEZ, DKA, NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1gxsA (A:)
qlqqqeddrilglpgqpngvafgmyggyvtiddnngralyywfqeadtadpaaaplvlwl
nggpgcssiglgamqelgafrvhtngeslllneyawnkaanilfaespagvgfsysntss
dlsmgddkmaqdtytflvkwferfphynyrefyiagesghfipqlsqvvyrnrnnspfin
fqgllvssgltndhedmigmfeswwhhglisdetrdsglkvcpgtsfmhptpectevwnk
alaeqgninpytiytptcdrepspyqrrfw

    Sequence, based on observed residues (ATOM records): (download) 
    >1gxsA (A:)
qqeddrilglpgqpngvafgmyggyvtiddnngralyywfqeadtadpaaaplvlwlngg
pgcssiglgamqelgafrvhtngeslllneyawnkaanilfaespagvgfsysntssdls
mgddkmaqdtytflvkwferfphynyrefyiagesghfipqlsqvvyrnrnnspfinfqg
llvssgltndhedmigmfeswwhhglisdetrdsglkvcpgtsfmhptpectevwnkala
eqgninpytiytptcdrepspyqrrfw

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1gxsB (B:)
lppydpcavfnsinylnlpevqtalhanvsgiveypwtvcsntifdqwgqaaddllpvyr
eliqaglrvwvysgdtdsvvpvsstrrslaalelpvktswypwymapterevggwsvqye
gltyvtvrgaghlvpvhrpaqafllfkqflkgepmpae

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1gxsC (C:)
qlqqqeddrilglpgqpngvafgmyggyvtiddnngralyywfqeadtadpaaaplvlwl
nggpgcssiglgamqelgafrvhtngeslllneyawnkaanilfaespagvgfsysntss
dlsmgddkmaqdtytflvkwferfphynyrefyiagesghfipqlsqvvyrnrnnspfin
fqgllvssgltndhedmigmfeswwhhglisdetrdsglkvcpgtsfmhptpectevwnk
alaeqgninpytiytptcdrepspyqrrfw

    Sequence, based on observed residues (ATOM records): (download) 
    >1gxsC (C:)
qqeddrilglpgqpngvafgmyggyvtiddnngralyywfqeadtadpaaaplvlwlngg
pgcssiglgamqelgafrvhtngeslllneyawnkaanilfaespagvgfsysntssdls
mgddkmaqdtytflvkwferfphynyrefyiagesghfipqlsqvvyrnrnnspfinfqg
llvssgltndhedmigmfeswwhhglisdetrdsglkvcpgtsfmhptpectevwnkala
eqgninpytiytptcdrepspyqrrfw

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1gxsD (D:)
lppydpcavfnsinylnlpevqtalhanvsgiveypwtvcsntifdqwgqaaddllpvyr
eliqaglrvwvysgdtdsvvpvsstrrslaalelpvktswypwymapterevggwsvqye
gltyvtvrgaghlvpvhrpaqafllfkqflkgepmpae