PDB entry 1gxs

View 1gxs on RCSB PDB site
Description: crystal structure of hydroxynitrile lyase from sorghum bicolor in complex with inhibitor benzoic acid: a novel cyanogenic enzyme
Class: lyase
Keywords: hydroxynitrile lyase, inhibitor complex, cyanogenesis mechanism
Deposited on 2002-04-11, released 2002-10-01
The last revision prior to the SCOP 1.73 freeze date was dated 2003-04-01, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.165
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hydroxynitrile lyase
    Species: SORGHUM BICOLOR
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8W4X3
      • variant (10)
      • variant (78)
      • variant (111)
      • variant (202)
    Domains in SCOP 1.73: d1gxs.1
  • Chain 'B':
    Compound: hydroxynitrile lyase
    Species: SORGHUM BICOLOR
    Domains in SCOP 1.73: d1gxs.1
  • Chain 'C':
    Compound: hydroxynitrile lyase
    Species: SORGHUM BICOLOR
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8W4X3
      • variant (10)
      • variant (78)
      • variant (111)
      • variant (202)
    Domains in SCOP 1.73: d1gxs.2
  • Chain 'D':
    Compound: hydroxynitrile lyase
    Species: SORGHUM BICOLOR
    Domains in SCOP 1.73: d1gxs.2
  • Heterogens: NAG, BEZ, DKA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1gxsA (A:)
qlqqqeddrilglpgqpngvafgmyggyvtiddnngralyywfqeadtadpaaaplvlwl
nggpgcssiglgamqelgafrvhtngeslllneyawnkaanilfaespagvgfsysntss
dlsmgddkmaqdtytflvkwferfphynyrefyiagesghfipqlsqvvyrnrnnspfin
fqgllvssgltndhedmigmfeswwhhglisdetrdsglkvcpgtsfmhptpectevwnk
alaeqgninpytiytptcdrepspyqrrfw

    Sequence, based on observed residues (ATOM records): (download) 
    >1gxsA (A:)
qqeddrilglpgqpngvafgmyggyvtiddnngralyywfqeadtadpaaaplvlwlngg
pgcssiglgamqelgafrvhtngeslllneyawnkaanilfaespagvgfsysntssdls
mgddkmaqdtytflvkwferfphynyrefyiagesghfipqlsqvvyrnrnnspfinfqg
llvssgltndhedmigmfeswwhhglisdetrdsglkvcpgtsfmhptpectevwnkala
eqgninpytiytptcdrepspyqrrfw

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1gxsB (B:)
lppydpcavfnsinylnlpevqtalhanvsgiveypwtvcsntifdqwgqaaddllpvyr
eliqaglrvwvysgdtdsvvpvsstrrslaalelpvktswypwymapterevggwsvqye
gltyvtvrgaghlvpvhrpaqafllfkqflkgepmpae

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1gxsC (C:)
qlqqqeddrilglpgqpngvafgmyggyvtiddnngralyywfqeadtadpaaaplvlwl
nggpgcssiglgamqelgafrvhtngeslllneyawnkaanilfaespagvgfsysntss
dlsmgddkmaqdtytflvkwferfphynyrefyiagesghfipqlsqvvyrnrnnspfin
fqgllvssgltndhedmigmfeswwhhglisdetrdsglkvcpgtsfmhptpectevwnk
alaeqgninpytiytptcdrepspyqrrfw

    Sequence, based on observed residues (ATOM records): (download) 
    >1gxsC (C:)
qqeddrilglpgqpngvafgmyggyvtiddnngralyywfqeadtadpaaaplvlwlngg
pgcssiglgamqelgafrvhtngeslllneyawnkaanilfaespagvgfsysntssdls
mgddkmaqdtytflvkwferfphynyrefyiagesghfipqlsqvvyrnrnnspfinfqg
llvssgltndhedmigmfeswwhhglisdetrdsglkvcpgtsfmhptpectevwnkala
eqgninpytiytptcdrepspyqrrfw

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1gxsD (D:)
lppydpcavfnsinylnlpevqtalhanvsgiveypwtvcsntifdqwgqaaddllpvyr
eliqaglrvwvysgdtdsvvpvsstrrslaalelpvktswypwymapterevggwsvqye
gltyvtvrgaghlvpvhrpaqafllfkqflkgepmpae