SCOP 1.61: Structural Classification of Proteins

PDB entry 1gth

View 1gth on RCSB PDB site
Description: dihydropyrimidine dehydrogenase (dpd) from pig, ternary complex with nadph and 5-iodouracil
Deposited on 2002-01-15, released 2002-04-11
The last revision prior to the SCOP 1.61 freeze date was dated 2002-04-11, with a file datestamp of 2002-04-11.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.177
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Domains in SCOP 1.61: d1gtha1, d1gtha2, d1gtha3, d1gtha4, d1gtha5
Chain 'B':
Domains in SCOP 1.61: d1gthb1, d1gthb2, d1gthb3, d1gthb4, d1gthb5
Chain 'C':
Domains in SCOP 1.61: d1gthc1, d1gthc2, d1gthc3, d1gthc4, d1gthc5
Chain 'D':
Domains in SCOP 1.61: d1gthd1, d1gthd2, d1gthd3, d1gthd4, d1gthd5

PDB Chain Sequences:

Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)

>1gthA (A:)
apvlskdvadiesilalnprtqshaalhstlakkldkkhwkrnpdkncfhceklennfdd
ikhttlgergalreamrclkcadapcqkscpthldiksfitsisnknyygaakmifsdnp
lgltcgmvcptsdlcvggcnlyateegsinigglqqfasevfkamnipqirnpclpsqek
mpeaysakiallgagpasiscasflarlgysditifekqeyvgglstseipqfrlpydvv
nfeielmkdlgvkiicgkslseneitlntlkeegykaafigiglpepktddifqgltqdq
gfytskdflplvaksskagmcachsplpsirgavivlgagdtafdcatsalrcgarrvfl
vfrkgfvniravpeevelakeekceflpflsprkvivkggrivavqfvrteqdetgkwne
dedqivhlkadvvisafgsvlrdpkvkealspikfnrwdlpevdpetmqtsepwvfaggd
ivgmanttvesvndgkqaswyihkyiqaqygasvsakpelplfytpvdlvdisvemaglk
finpfglasaapttsssmirrafeagwgfaltktfsldkdivtnvsprivrgttsgpmyg
pgqssflnielisektaaywcqsvtelkadfpdniviasimcsynkndwmelsrkaeasg
adalelnlscphgmgergmglacgqdpelvrnicrwvrqavqipffakltpnvtdivsia
raakeggadgvtatntvsglmglkadgtpwpavgagkrttyggvsgtairpialravtti
aralpgfpilatggidsaesglqflhsgasvlqvcsavqnqdftviqdyctglkallylk
sieelqgwdgqspgteshqkgkpvpriaelmgkklpnfgpyleqrkkiiaeekmrlkeqn
aafpplerkpfipkkpipaikdvigkalqylgtfgelsnieqvvavideemcincgkcym
tcndsgyqaiqfdpethlptvtdtctgctlclsvcpiidcirmvsrttpyepkrglpla

Chain 'B':
Sequence, based on SEQRES records: (download)

>1gthB (B:)
apvlskdvadiesilalnprtqshaalhstlakkldkkhwkrnpdkncfhceklennfdd
ikhttlgergalreamrclkcadapcqkscpthldiksfitsisnknyygaakmifsdnp
lgltcgmvcptsdlcvggcnlyateegsinigglqqfasevfkamnipqirnpclpsqek
mpeaysakiallgagpasiscasflarlgysditifekqeyvgglstseipqfrlpydvv
nfeielmkdlgvkiicgkslseneitlntlkeegykaafigiglpepktddifqgltqdq
gfytskdflplvaksskagmcachsplpsirgavivlgagdtafdcatsalrcgarrvfl
vfrkgfvniravpeevelakeekceflpflsprkvivkggrivavqfvrteqdetgkwne
dedqivhlkadvvisafgsvlrdpkvkealspikfnrwdlpevdpetmqtsepwvfaggd
ivgmanttvesvndgkqaswyihkyiqaqygasvsakpelplfytpvdlvdisvemaglk
finpfglasaapttsssmirrafeagwgfaltktfsldkdivtnvsprivrgttsgpmyg
pgqssflnielisektaaywcqsvtelkadfpdniviasimcsynkndwmelsrkaeasg
adalelnlscphgmgergmglacgqdpelvrnicrwvrqavqipffakltpnvtdivsia
raakeggadgvtatntvsglmglkadgtpwpavgagkrttyggvsgtairpialravtti
aralpgfpilatggidsaesglqflhsgasvlqvcsavqnqdftviqdyctglkallylk
sieelqgwdgqspgteshqkgkpvpriaelmgkklpnfgpyleqrkkiiaeekmrlkeqn
aafpplerkpfipkkpipaikdvigkalqylgtfgelsnieqvvavideemcincgkcym
tcndsgyqaiqfdpethlptvtdtctgctlclsvcpiidcirmvsrttpyepkrglpla

Sequence, based on observed residues (ATOM records): (download)

>1gthB (B:)
apvlskdvadiesilalnprtqshaalhstlakkldkkhwkrnpdkncfhceklennfdd
ikhttlgergalreamrclkcadapcqkscpthldiksfitsisnknyygaakmifsdnp
lgltcgmvcptsdlcvggcnlyateegsinigglqqfasevfkamnipqirnpclpsqek
mpeaysakiallgagpasiscasflarlgysditifekqeyvgglstseipqfrlpydvv
nfeielmkdlgvkiicgkslseneitlntlkeegykaafigiglpepktddifqgltqdq
gfytskdflplvaksskagmcachsplpsirgavivlgagdtafdcatsalrcgarrvfl
vfrkgfvniravpeevelakeekceflpflsprkvivkggrivavqfvrteqdetgkwne
dedqivhlkadvvisafgsvlrdpkvkealspikfnrwdlpevdpetmqtsepwvfaggd
ivgmanttvesvndgkqaswyihkyiqaqygasvsakpelplfytpvdlvdisvemaglk
finpfglasaapttsssmirrafeagwgfaltktfsldkdivtnvsprivrgttsgpmyg
pgqssflnielisektaaywcqsvtelkadfpdniviasimcsynkndwmelsrkaeasg
adalelnlscphgmgergmglacgqdpelvrnicrwvrqavqipffakltpnvtdivsia
raakeggadgvtatntvsglmglkadgtpwpavgagkrttyggvsgtairpialravtti
aralpgfpilatggidsaesglqflhsgasvlqvcsavqnqdftviqdyctglkallylk
sieelqgwdgqspgteshqkgkpvpriaelmgkklpnfgpyleqrkkiiaeekmrlkeqe
rkpfipkkpipaikdvigkalqylgtfgelsnieqvvavideemcincgkcymtcndsgy
qaiqfdpethlptvtdtctgctlclsvcpiidcirmvsrttpyepkrglpla

Chain 'C':
Sequence, based on SEQRES records: (download)

>1gthC (C:)
apvlskdvadiesilalnprtqshaalhstlakkldkkhwkrnpdkncfhceklennfdd
ikhttlgergalreamrclkcadapcqkscpthldiksfitsisnknyygaakmifsdnp
lgltcgmvcptsdlcvggcnlyateegsinigglqqfasevfkamnipqirnpclpsqek
mpeaysakiallgagpasiscasflarlgysditifekqeyvgglstseipqfrlpydvv
nfeielmkdlgvkiicgkslseneitlntlkeegykaafigiglpepktddifqgltqdq
gfytskdflplvaksskagmcachsplpsirgavivlgagdtafdcatsalrcgarrvfl
vfrkgfvniravpeevelakeekceflpflsprkvivkggrivavqfvrteqdetgkwne
dedqivhlkadvvisafgsvlrdpkvkealspikfnrwdlpevdpetmqtsepwvfaggd
ivgmanttvesvndgkqaswyihkyiqaqygasvsakpelplfytpvdlvdisvemaglk
finpfglasaapttsssmirrafeagwgfaltktfsldkdivtnvsprivrgttsgpmyg
pgqssflnielisektaaywcqsvtelkadfpdniviasimcsynkndwmelsrkaeasg
adalelnlscphgmgergmglacgqdpelvrnicrwvrqavqipffakltpnvtdivsia
raakeggadgvtatntvsglmglkadgtpwpavgagkrttyggvsgtairpialravtti
aralpgfpilatggidsaesglqflhsgasvlqvcsavqnqdftviqdyctglkallylk
sieelqgwdgqspgteshqkgkpvpriaelmgkklpnfgpyleqrkkiiaeekmrlkeqn
aafpplerkpfipkkpipaikdvigkalqylgtfgelsnieqvvavideemcincgkcym
tcndsgyqaiqfdpethlptvtdtctgctlclsvcpiidcirmvsrttpyepkrglpla

Sequence, based on observed residues (ATOM records): (download)

>1gthC (C:)
apvlskdvadiesilalnprtqshaalhstlakkldkkhwkrnpdkncfhceklennfdd
ikhttlgergalreamrclkcadapcqkscpthldiksfitsisnknyygaakmifsdnp
lgltcgmvcptsdlcvggcnlyateegsinigglqqfasevfkamnipqirnpclpsqek
mpeaysakiallgagpasiscasflarlgysditifekqeyvgglstseipqfrlpydvv
nfeielmkdlgvkiicgkslseneitlntlkeegykaafigiglpepktddifqgltqdq
gfytskdflplvaksskagmcachsplpsirgavivlgagdtafdcatsalrcgarrvfl
vfrkgfvniravpeevelakeekceflpflsprkvivkggrivavqfvrteqdetgkwne
dedqivhlkadvvisafgsvlrdpkvkealspikfnrwdlpevdpetmqtsepwvfaggd
ivgmanttvesvndgkqaswyihkyiqaqygasvsakpelplfytpvdlvdisvemaglk
finpfglasaapttsssmirrafeagwgfaltktfsldkdivtnvsprivrgttsgpmyg
pgqssflnielisektaaywcqsvtelkadfpdniviasimcsynkndwmelsrkaeasg
adalelnlscphgmgergmglacgqdpelvrnicrwvrqavqipffakltpnvtdivsia
raakeggadgvtatntvsglmglkadgtpwpavgagkrttyggvsgtairpialravtti
aralpgfpilatggidsaesglqflhsgasvlqvcsavqnqdftviqdyctglkallylk
sieelqgwdgqspgteshqkgkpvpriaelmgkklpnfgpyleqrkkiiaeekmrlkeqn
alerkpfipkkpipaikdvigkalqylgtfgelsnieqvvavideemcincgkcymtcnd
sgyqaiqfdpethlptvtdtctgctlclsvcpiidcirmvsrttpyepkrglpla

Chain 'D':
Sequence; same for both SEQRES and ATOM records: (download)

>1gthD (D:)
apvlskdvadiesilalnprtqshaalhstlakkldkkhwkrnpdkncfhceklennfdd
ikhttlgergalreamrclkcadapcqkscpthldiksfitsisnknyygaakmifsdnp
lgltcgmvcptsdlcvggcnlyateegsinigglqqfasevfkamnipqirnpclpsqek
mpeaysakiallgagpasiscasflarlgysditifekqeyvgglstseipqfrlpydvv
nfeielmkdlgvkiicgkslseneitlntlkeegykaafigiglpepktddifqgltqdq
gfytskdflplvaksskagmcachsplpsirgavivlgagdtafdcatsalrcgarrvfl
vfrkgfvniravpeevelakeekceflpflsprkvivkggrivavqfvrteqdetgkwne
dedqivhlkadvvisafgsvlrdpkvkealspikfnrwdlpevdpetmqtsepwvfaggd
ivgmanttvesvndgkqaswyihkyiqaqygasvsakpelplfytpvdlvdisvemaglk
finpfglasaapttsssmirrafeagwgfaltktfsldkdivtnvsprivrgttsgpmyg
pgqssflnielisektaaywcqsvtelkadfpdniviasimcsynkndwmelsrkaeasg
adalelnlscphgmgergmglacgqdpelvrnicrwvrqavqipffakltpnvtdivsia
raakeggadgvtatntvsglmglkadgtpwpavgagkrttyggvsgtairpialravtti
aralpgfpilatggidsaesglqflhsgasvlqvcsavqnqdftviqdyctglkallylk
sieelqgwdgqspgteshqkgkpvpriaelmgkklpnfgpyleqrkkiiaeekmrlkeqn
aafpplerkpfipkkpipaikdvigkalqylgtfgelsnieqvvavideemcincgkcym
tcndsgyqaiqfdpethlptvtdtctgctlclsvcpiidcirmvsrttpyepkrglpla