PDB entry 1gpw

View 1gpw on RCSB PDB site
Description: structural evidence for ammonia tunneling across the (beta/alpha)8 barrel of the imidazole glycerol phosphate synthase bienzyme complex.
Class: lyase/transferase
Keywords: lyase/transferase, complex (lyase/transferase), histidine biosynthesis, glutaminase, glutamine amidotransferase, cyclase, ammonia channel
Deposited on 2001-11-12, released 2002-02-10
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.226
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hisf protein
    Species: Thermotoga maritima [TaxId:2336]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9X0C6 (0-252)
      • engineered mutation (10)
    Domains in SCOPe 2.05: d1gpwa_
  • Chain 'B':
    Compound: amidotransferase hish
    Species: Thermotoga maritima [TaxId:2336]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1gpwb_
  • Chain 'C':
    Compound: hisf protein
    Species: Thermotoga maritima [TaxId:2336]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9X0C6 (0-252)
      • engineered mutation (10)
    Domains in SCOPe 2.05: d1gpwc_
  • Chain 'D':
    Compound: amidotransferase hish
    Species: Thermotoga maritima [TaxId:2336]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1gpwd_
  • Chain 'E':
    Compound: hisf protein
    Species: Thermotoga maritima [TaxId:2336]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9X0C6 (0-252)
      • engineered mutation (10)
    Domains in SCOPe 2.05: d1gpwe_
  • Chain 'F':
    Compound: amidotransferase hish
    Species: Thermotoga maritima [TaxId:2336]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1gpwf_
  • Heterogens: PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1gpwA (A:)
mlakriiaclnvkdgrvvkgtnfenlrdsgdpvelgkfyseigidelvflditasvekrk
tmlelvekvaeqidipftvgggihdfetaselilrgadkvsintaavenpslitqiaqtf
gsqavvvaidakrvdgefmvftysgkkntgillrdwvvevekrgageilltsidrdgtks
gydtemirfvrplttlpiiasggagkmehfleaflagadaalaasvfhfreidvrelkey
lkkhgvnvrlegl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1gpwB (B:)
mrigiisvgpgnimnlyrgvkrasenfedvsielvesprndlydllfipgvghfgegmrr
lrendlidfvrkhvederyvvgvclgmqllfeeseeapgvkglsliegnvvklrsrrlph
mgwnevifkdtfpngyyyfvhtyravceeehvlgtteydgeifpsavrkgrilgfqfhpe
ksskigrkllekviecslsrr

    Sequence, based on observed residues (ATOM records): (download) 
    >1gpwB (B:)
mrigiisvgpgnimnlyrgvkrasenfedvsielvesprndlydllfipgvghfgegmrr
lrendlidfvrkhvederyvvgvclgmqllfeeseeapgvkglsliegnvvklrsrrlph
mgwnevifkdtfpngyyyfvhtyravceeehvlgtteydgeifpsavrkgrilgfqfhpe
ksskigrkllekviecslsr

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1gpwC (C:)
mlakriiaclnvkdgrvvkgtnfenlrdsgdpvelgkfyseigidelvflditasvekrk
tmlelvekvaeqidipftvgggihdfetaselilrgadkvsintaavenpslitqiaqtf
gsqavvvaidakrvdgefmvftysgkkntgillrdwvvevekrgageilltsidrdgtks
gydtemirfvrplttlpiiasggagkmehfleaflagadaalaasvfhfreidvrelkey
lkkhgvnvrlegl

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1gpwD (D:)
mrigiisvgpgnimnlyrgvkrasenfedvsielvesprndlydllfipgvghfgegmrr
lrendlidfvrkhvederyvvgvclgmqllfeeseeapgvkglsliegnvvklrsrrlph
mgwnevifkdtfpngyyyfvhtyravceeehvlgtteydgeifpsavrkgrilgfqfhpe
ksskigrkllekviecslsrr

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1gpwE (E:)
mlakriiaclnvkdgrvvkgtnfenlrdsgdpvelgkfyseigidelvflditasvekrk
tmlelvekvaeqidipftvgggihdfetaselilrgadkvsintaavenpslitqiaqtf
gsqavvvaidakrvdgefmvftysgkkntgillrdwvvevekrgageilltsidrdgtks
gydtemirfvrplttlpiiasggagkmehfleaflagadaalaasvfhfreidvrelkey
lkkhgvnvrlegl

    Sequence, based on observed residues (ATOM records): (download) 
    >1gpwE (E:)
mlakriiaclnvkdgrvvknfenlrdsgdpvelgkfyseigidelvflditasvekrktm
lelvekvaeqidipftvgggihdfetaselilrgadkvsintaavenpslitqiaqtfgs
qavvvaidakrvdgefmvftysgkkntgillrdwvvevekrgageilltsidrdgtksgy
dtemirfvrplttlpiiasggagkmehfleaflagadaalaasvfhfreidvrelkeylk
khgvnvrlegl

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1gpwF (F:)
mrigiisvgpgnimnlyrgvkrasenfedvsielvesprndlydllfipgvghfgegmrr
lrendlidfvrkhvederyvvgvclgmqllfeeseeapgvkglsliegnvvklrsrrlph
mgwnevifkdtfpngyyyfvhtyravceeehvlgtteydgeifpsavrkgrilgfqfhpe
ksskigrkllekviecslsrr