PDB entry 1gkd

View 1gkd on RCSB PDB site
Description: mmp9 active site mutant-inhibitor complex
Class: hydrolase
Keywords: matrix metalloprotease, hydrolase, glycoprotein
Deposited on 2001-08-10, released 2002-05-16
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.212
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 92 kda type IV collagenase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1GKD
      • engineered mutation (121)
    • Uniprot P14780 (110-162)
    Domains in SCOPe 2.01: d1gkda_
  • Chain 'B':
    Compound: 92 kda type IV collagenase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1GKD
      • engineered mutation (121)
    • Uniprot P14780 (110-162)
    Domains in SCOPe 2.01: d1gkdb_
  • Heterogens: CA, STN, BUM, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1gkdA (A:)
mfqtfegdlkwhhhnitywiqnysedlpraviddafarafalwsavtpltftrvysrdad
iviqfgvaehgdgypfdgkdgllahafppgpgiqgdahfdddelwslgkgqgyslflvaa
hqfghalgldhssvpealmypmyrftegpplhkddvngirhly

    Sequence, based on observed residues (ATOM records): (download) 
    >1gkdA (A:)
fegdlkwhhhnitywiqnysedlpraviddafarafalwsavtpltftrvysrdadiviq
fgvaehgdgypfdgkdgllahafppgpgiqgdahfdddelwslgkgqgyslflvaahqfg
halgldhssvpealmypmyrftegpplhkddvngirhly

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1gkdB (B:)
mfqtfegdlkwhhhnitywiqnysedlpraviddafarafalwsavtpltftrvysrdad
iviqfgvaehgdgypfdgkdgllahafppgpgiqgdahfdddelwslgkgqgyslflvaa
hqfghalgldhssvpealmypmyrftegpplhkddvngirhly

    Sequence, based on observed residues (ATOM records): (download) 
    >1gkdB (B:)
lkwhhhnitywiqnysedlpraviddafarafalwsavtpltftrvysrdadiviqfgva
ehgdgypfdgkdgllahafppgpgiqgdahfdddelwslgkgqgyslflvaahqfghalg
ldhssvpealmypmyrftegpplhkddvngirhly