PDB entry 1gkc

View 1gkc on RCSB PDB site
Description: mmp9-inhibitor complex
Class: hydrolase/hydrolase inhibitor
Keywords: matrix metalloprotease, hydrolase, glycoprotein, hydrolase-hydrolase inhibitor complex
Deposited on 2001-08-10, released 2002-05-16
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-06-21.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.207
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 92 kda type IV collagenase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1GKC
    • Uniprot P14780 (110-162)
    Domains in SCOPe 2.06: d1gkca_
  • Chain 'B':
    Compound: 92 kda type IV collagenase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1GKC
    • Uniprot P14780 (110-162)
    Domains in SCOPe 2.06: d1gkcb_
  • Heterogens: CA, NFH, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1gkcA (A:)
mfqtfegdlkwhhhnitywiqnysedlpraviddafarafalwsavtpltftrvysrdad
iviqfgvaehgdgypfdgkdgllahafppgpgiqgdahfdddelwslgkgqgyslflvaa
hefghalgldhssvpealmypmyrftegpplhkddvngirhly

    Sequence, based on observed residues (ATOM records): (download) 
    >1gkcA (A:)
fegdlkwhhhnitywiqnysedlpraviddafarafalwsavtpltftrvysrdadiviq
fgvaehgdgypfdgkdgllahafppgpgiqgdahfdddelwslgkgqgyslflvaahefg
halgldhssvpealmypmyrftegpplhkddvngirhly

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1gkcB (B:)
mfqtfegdlkwhhhnitywiqnysedlpraviddafarafalwsavtpltftrvysrdad
iviqfgvaehgdgypfdgkdgllahafppgpgiqgdahfdddelwslgkgqgyslflvaa
hefghalgldhssvpealmypmyrftegpplhkddvngirhly

    Sequence, based on observed residues (ATOM records): (download) 
    >1gkcB (B:)
dlkwhhhnitywiqnysedlpraviddafarafalwsavtpltftrvysrdadiviqfgv
aehgdgypfdgkdgllahafppgpgiqgdahfdddelwslgkgqgyslflvaahefghal
gldhssvpealmypmyrftegpplhkddvngirhly