PDB entry 1gj6
View 1gj6 on RCSB PDB site
Description: engineering inhibitors highly selective for the s1 sites of ser190 trypsin-like serine protease drug targets
Class: hydrolase
Keywords: selectivity at S1, H2O displacement, uPA, tPA, Ser190/Ala190 protease, structure-based drug design
Deposited on
2001-04-27, released
2002-04-27
The last revision prior to the SCOP 1.75 freeze date was dated
2002-04-27, with a file datestamp of
2007-07-20.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: 0.187
AEROSPACI score: 0.72
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: beta-trypsin
Species: BOS TAURUS
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d1gj6a_ - Heterogens: CA, 132, HOH