PDB entry 1ghp

View 1ghp on RCSB PDB site
Description: structures of the acyl-enzyme complex of the staphylococcus aureus beta-lactamase mutant glu166asp:asn170gln with degraded benzylpenicillin
Class: hydrolase
Keywords: hydrolase, antibiotic resistance, beta-lactam hydrolysis, benzylpenicillin, cephaloridine
Deposited on 2000-12-21, released 2001-04-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.76 Å
R-factor: 0.185
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: BLAZ
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00807 (1-257)
      • engineered (133)
      • engineered (137)
    Domains in SCOPe 2.08: d1ghpa_
  • Heterogens: SO4, PNM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1ghpA (A:)
mkelndlekkynahigvyaldtksgkevkfnsdkrfayastskainsailleqvpynkln
kkvhinkddivayspilekyvgkditlkalieasmtysdntannkiikeiggikkvkqrl
kelgdkvtnpvrydielqyyspkskkdtstpaafgktlnkliangklskenkkflldlml
nnksgdtlikdgvpkdykvadksgqaityasrndvafvypkgqsepivlviftnkdnksd
kpndklisetaksvmkef

    Sequence, based on observed residues (ATOM records): (download) 
    >1ghpA (A:)
kelndlekkynahigvyaldtksgkevkfnsdkrfayastskainsailleqvpynklnk
kvhinkddivayspilekyvgkditlkalieasmtysdntannkiikeiggikkvkqrlk
elgdkvtnpvrydielqyyspkskkdtstpaafgktlnkliangklskenkkflldlmln
nksgdtlikdgvpkdykvadksgqaityasrndvafvypkgqsepivlviftnkdnksdk
pndklisetaksvmkef