PDB entry 1gfy

View 1gfy on RCSB PDB site
Description: residue 259 is a key determinant of substrate specificity of protein-tyrosine phosphatase 1b and alpha
Class: hydrolase
Keywords: hydrolase
Deposited on 2000-06-26, released 2000-07-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-03-07, with a file datestamp of 2018-03-02.
Experiment type: XRAY
Resolution: 2.13 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protein (protein-tyrosine phosphatase 1b)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P18031 (Start-297)
      • engineered (46-47)
      • conflict (150)
      • conflict (251)
      • engineered (257-258)
    Domains in SCOPe 2.08: d1gfya_
  • Heterogens: COL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1gfyA (A:)
memekefeqidksgswaaiyqdirheasdfpcrvaklpknknrnryvnvspfdhsriklh
qedndyinaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvvmlnrvmekgslk
caqywpqkeekemifedtnlkltlisediktyytvrqlelenlttqetreilhfhyttwp
dfgvpespasflnflfkvresgslspehgpvvvhcsagigrsgtfcladtclllmdkrkd
pssvdikkvlldmrkfrcqliqtadqlrfsylaviegakfimgdssvqdqwkelshed

    Sequence, based on observed residues (ATOM records): (download) 
    >1gfyA (A:)
mekefeqidksgswaaiyqdirheasdfpcrvaklpknknrnryvnvspfdhsriklhqe
dndyinaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvvmlnrvmekgslkca
qywpqkeekemifedtnlkltlisediktyytvrqlelenlttqetreilhfhyttwpdf
gvpespasflnflfkvresgslspehgpvvvhcsagigrsgtfcladtclllmdkrkdps
svdikkvlldmrkfrcqliqtadqlrfsylaviegakfimgdssvqdqwkelshed