PDB entry 1gcq

View 1gcq on RCSB PDB site
Description: crystal structure of vav and grb2 sh3 domains
Class: signaling protein/signaling protein
Keywords: SH3 domain, PROTEIN-PROTEIN COMPLEX, Grb2,Vav, SIGNALING PROTEIN/SIGNALING PROTEIN COMPLEX
Deposited on 2000-08-08, released 2001-08-08
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.68 Å
R-factor: 0.201
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Growth factor receptor-bound protein 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62993 (2-End)
      • cloning artifact (1)
    Domains in SCOPe 2.02: d1gcqa_
  • Chain 'B':
    Compound: Growth factor receptor-bound protein 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d1gcqb_
  • Chain 'C':
    Compound: vav proto-oncogene
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27870 (4-End)
      • cloning artifact (0-3)
    Domains in SCOPe 2.02: d1gcqc_
  • Heterogens: MRD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1gcqA (A:)
gstyvqalfdfdpqedgelgfrrgdfihvmdnsdpnwwkgachgqtgmfprnyvtpvnrn
v

    Sequence, based on observed residues (ATOM records): (download) 
    >1gcqA (A:)
styvqalfdfdpqedgelgfrrgdfihvmdnsdpnwwkgachgqtgmfprnyvtpv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1gcqB (B:)
gstyvqalfdfdpqedgelgfrrgdfihvmdnsdpnwwkgachgqtgmfprnyvtpvnrn
v

    Sequence, based on observed residues (ATOM records): (download) 
    >1gcqB (B:)
tyvqalfdfdpqedgelgfrrgdfihvmdnsdpnwwkgachgqtgmfprnyvtpvnr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1gcqC (C:)
gshmpkmevfqeyygippppgafgpflrlnpgdiveltkaeaehnwwegrntatnevgwf
pcnrvhpyvh

    Sequence, based on observed residues (ATOM records): (download) 
    >1gcqC (C:)
gshmpkmevfqeyygippppgafgpflrlnpgdiveltkaeaehnwwegrntatnevgwf
pcnrvhpyv