PDB entry 1gc3

View 1gc3 on RCSB PDB site
Description: thermus thermophilus aspartate aminotransferase tetra mutant 2 complexed with tryptophan
Class: transferase
Keywords: Aminotransferase, Dual-substrate enzyme, Pyridoxal enzyme, TRANSFERASE
Deposited on 2000-07-18, released 2001-09-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-10-16, with a file datestamp of 2019-10-11.
Experiment type: XRAY
Resolution: 3.3 Å
R-factor: N/A
AEROSPACI score: 0.09 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: aspartate aminotransferase
    Species: Thermus thermophilus [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q56232
      • engineered (13)
      • engineered (15)
      • engineered (100)
      • engineered (260)
    Domains in SCOPe 2.08: d1gc3a_
  • Chain 'B':
    Compound: aspartate aminotransferase
    Species: Thermus thermophilus [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q56232
      • engineered (13)
      • engineered (15)
      • engineered (100)
      • engineered (260)
    Domains in SCOPe 2.08: d1gc3b_
  • Chain 'C':
    Compound: aspartate aminotransferase
    Species: Thermus thermophilus [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q56232
      • engineered (13)
      • engineered (15)
      • engineered (100)
      • engineered (260)
    Domains in SCOPe 2.08: d1gc3c_
  • Chain 'D':
    Compound: aspartate aminotransferase
    Species: Thermus thermophilus [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q56232
      • engineered (13)
      • engineered (15)
      • engineered (100)
      • engineered (260)
    Domains in SCOPe 2.08: d1gc3d_
  • Chain 'E':
    Compound: aspartate aminotransferase
    Species: Thermus thermophilus [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q56232
      • engineered (13)
      • engineered (15)
      • engineered (100)
      • engineered (260)
    Domains in SCOPe 2.08: d1gc3e_
  • Chain 'F':
    Compound: aspartate aminotransferase
    Species: Thermus thermophilus [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q56232
      • engineered (13)
      • engineered (15)
      • engineered (100)
      • engineered (260)
    Domains in SCOPe 2.08: d1gc3f_
  • Chain 'G':
    Compound: aspartate aminotransferase
    Species: Thermus thermophilus [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q56232
      • engineered (13)
      • engineered (15)
      • engineered (100)
      • engineered (260)
    Domains in SCOPe 2.08: d1gc3g_
  • Chain 'H':
    Compound: aspartate aminotransferase
    Species: Thermus thermophilus [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q56232 (0-End)
      • engineered (13)
      • engineered (15)
      • engineered (100)
      • engineered (260)
    Domains in SCOPe 2.08: d1gc3h_
  • Heterogens: TRP, PLP

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1gc3A (A:)
    mrglsrrvqamkpdavvavnakalelrrqgvdlvaltagepdfdtpehvkeaarralaqg
    ktkyappagipelrealaekfrrenglsvtpeetivtvggsqalfnlfqaildpgdeviv
    lspywvsypemvrfaggvvvevetlpeegfvpdpervrraitprtkalvvnspnnptgav
    ypkevlealarlavehdfylvsdeiyehllyegehfspgrvapehtltvngaakafamtg
    wrigyacgpkevikamasvsrqsttspdtiaqwatlealtnqeasrafvemareayrrrr
    dlllegltalglkavrpsgafyvlmdtspiapdevraaerlleagvavvpgtdfaafghv
    rlsyatseenlrkalerfarvlgra
    

    Sequence, based on observed residues (ATOM records): (download)
    >1gc3A (A:)
    mrglsrrvqamkpdavvavnakalelrrqgvdlvaltagepdfdtpehvkeaarralaqg
    ktkyappagipelrealaekfrrenglsvtpeetivtvggsqalfnlfqaildpgdeviv
    lspywvsypemvrfaggvvvevetlpeegfvpdpervrraitprtkalvvnspnnptgav
    ypkevlealarlavehdfylvsdeiyehllyegehfspgrvapehtltvngaakafamtg
    wrigyacgpkevikamasvsrqsttspdtiaqwatlealtnqeasrafvemareayrrrr
    dlllegltalglkavrpsgafyvlmdtspiapdevraaerlleagvavvpgtdfaafghv
    rlsyatseenlrkalerfarvl
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1gc3B (B:)
    mrglsrrvqamkpdavvavnakalelrrqgvdlvaltagepdfdtpehvkeaarralaqg
    ktkyappagipelrealaekfrrenglsvtpeetivtvggsqalfnlfqaildpgdeviv
    lspywvsypemvrfaggvvvevetlpeegfvpdpervrraitprtkalvvnspnnptgav
    ypkevlealarlavehdfylvsdeiyehllyegehfspgrvapehtltvngaakafamtg
    wrigyacgpkevikamasvsrqsttspdtiaqwatlealtnqeasrafvemareayrrrr
    dlllegltalglkavrpsgafyvlmdtspiapdevraaerlleagvavvpgtdfaafghv
    rlsyatseenlrkalerfarvlgra
    

    Sequence, based on observed residues (ATOM records): (download)
    >1gc3B (B:)
    mrglsrrvqamkpdavvavnakalelrrqgvdlvaltagepdfdtpehvkeaarralaqg
    ktkyappagipelrealaekfrrenglsvtpeetivtvggsqalfnlfqaildpgdeviv
    lspywvsypemvrfaggvvvevetlpeegfvpdpervrraitprtkalvvnspnnptgav
    ypkevlealarlavehdfylvsdeiyehllyegehfspgrvapehtltvngaakafamtg
    wrigyacgpkevikamasvsrqsttspdtiaqwatlealtnqeasrafvemareayrrrr
    dlllegltalglkavrpsgafyvlmdtspiapdevraaerlleagvavvpgtdfaafghv
    rlsyatseenlrkalerfarvl
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >1gc3C (C:)
    mrglsrrvqamkpdavvavnakalelrrqgvdlvaltagepdfdtpehvkeaarralaqg
    ktkyappagipelrealaekfrrenglsvtpeetivtvggsqalfnlfqaildpgdeviv
    lspywvsypemvrfaggvvvevetlpeegfvpdpervrraitprtkalvvnspnnptgav
    ypkevlealarlavehdfylvsdeiyehllyegehfspgrvapehtltvngaakafamtg
    wrigyacgpkevikamasvsrqsttspdtiaqwatlealtnqeasrafvemareayrrrr
    dlllegltalglkavrpsgafyvlmdtspiapdevraaerlleagvavvpgtdfaafghv
    rlsyatseenlrkalerfarvlgra
    

    Sequence, based on observed residues (ATOM records): (download)
    >1gc3C (C:)
    mrglsrrvqamkpdavvavnakalelrrqgvdlvaltagepdfdtpehvkeaarralaqg
    ktkyappagipelrealaekfrrenglsvtpeetivtvggsqalfnlfqaildpgdeviv
    lspywvsypemvrfaggvvvevetlpeegfvpdpervrraitprtkalvvnspnnptgav
    ypkevlealarlavehdfylvsdeiyehllyegehfspgrvapehtltvngaakafamtg
    wrigyacgpkevikamasvsrqsttspdtiaqwatlealtnqeasrafvemareayrrrr
    dlllegltalglkavrpsgafyvlmdtspiapdevraaerlleagvavvpgtdfaafghv
    rlsyatseenlrkalerfarvl
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1gc3D (D:)
    mrglsrrvqamkpdavvavnakalelrrqgvdlvaltagepdfdtpehvkeaarralaqg
    ktkyappagipelrealaekfrrenglsvtpeetivtvggsqalfnlfqaildpgdeviv
    lspywvsypemvrfaggvvvevetlpeegfvpdpervrraitprtkalvvnspnnptgav
    ypkevlealarlavehdfylvsdeiyehllyegehfspgrvapehtltvngaakafamtg
    wrigyacgpkevikamasvsrqsttspdtiaqwatlealtnqeasrafvemareayrrrr
    dlllegltalglkavrpsgafyvlmdtspiapdevraaerlleagvavvpgtdfaafghv
    rlsyatseenlrkalerfarvlgra
    

    Sequence, based on observed residues (ATOM records): (download)
    >1gc3D (D:)
    mrglsrrvqamkpdavvavnakalelrrqgvdlvaltagepdfdtpehvkeaarralaqg
    ktkyappagipelrealaekfrrenglsvtpeetivtvggsqalfnlfqaildpgdeviv
    lspywvsypemvrfaggvvvevetlpeegfvpdpervrraitprtkalvvnspnnptgav
    ypkevlealarlavehdfylvsdeiyehllyegehfspgrvapehtltvngaakafamtg
    wrigyacgpkevikamasvsrqsttspdtiaqwatlealtnqeasrafvemareayrrrr
    dlllegltalglkavrpsgafyvlmdtspiapdevraaerlleagvavvpgtdfaafghv
    rlsyatseenlrkalerfarvl
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >1gc3E (E:)
    mrglsrrvqamkpdavvavnakalelrrqgvdlvaltagepdfdtpehvkeaarralaqg
    ktkyappagipelrealaekfrrenglsvtpeetivtvggsqalfnlfqaildpgdeviv
    lspywvsypemvrfaggvvvevetlpeegfvpdpervrraitprtkalvvnspnnptgav
    ypkevlealarlavehdfylvsdeiyehllyegehfspgrvapehtltvngaakafamtg
    wrigyacgpkevikamasvsrqsttspdtiaqwatlealtnqeasrafvemareayrrrr
    dlllegltalglkavrpsgafyvlmdtspiapdevraaerlleagvavvpgtdfaafghv
    rlsyatseenlrkalerfarvlgra
    

    Sequence, based on observed residues (ATOM records): (download)
    >1gc3E (E:)
    mrglsrrvqamkpdavvavnakalelrrqgvdlvaltagepdfdtpehvkeaarralaqg
    ktkyappagipelrealaekfrrenglsvtpeetivtvggsqalfnlfqaildpgdeviv
    lspywvsypemvrfaggvvvevetlpeegfvpdpervrraitprtkalvvnspnnptgav
    ypkevlealarlavehdfylvsdeiyehllyegehfspgrvapehtltvngaakafamtg
    wrigyacgpkevikamasvsrqsttspdtiaqwatlealtnqeasrafvemareayrrrr
    dlllegltalglkavrpsgafyvlmdtspiapdevraaerlleagvavvpgtdfaafghv
    rlsyatseenlrkalerfarvl
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >1gc3F (F:)
    mrglsrrvqamkpdavvavnakalelrrqgvdlvaltagepdfdtpehvkeaarralaqg
    ktkyappagipelrealaekfrrenglsvtpeetivtvggsqalfnlfqaildpgdeviv
    lspywvsypemvrfaggvvvevetlpeegfvpdpervrraitprtkalvvnspnnptgav
    ypkevlealarlavehdfylvsdeiyehllyegehfspgrvapehtltvngaakafamtg
    wrigyacgpkevikamasvsrqsttspdtiaqwatlealtnqeasrafvemareayrrrr
    dlllegltalglkavrpsgafyvlmdtspiapdevraaerlleagvavvpgtdfaafghv
    rlsyatseenlrkalerfarvlgra
    

    Sequence, based on observed residues (ATOM records): (download)
    >1gc3F (F:)
    mrglsrrvqamkpdavvavnakalelrrqgvdlvaltagepdfdtpehvkeaarralaqg
    ktkyappagipelrealaekfrrenglsvtpeetivtvggsqalfnlfqaildpgdeviv
    lspywvsypemvrfaggvvvevetlpeegfvpdpervrraitprtkalvvnspnnptgav
    ypkevlealarlavehdfylvsdeiyehllyegehfspgrvapehtltvngaakafamtg
    wrigyacgpkevikamasvsrqsttspdtiaqwatlealtnqeasrafvemareayrrrr
    dlllegltalglkavrpsgafyvlmdtspiapdevraaerlleagvavvpgtdfaafghv
    rlsyatseenlrkalerfarvl
    

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >1gc3G (G:)
    mrglsrrvqamkpdavvavnakalelrrqgvdlvaltagepdfdtpehvkeaarralaqg
    ktkyappagipelrealaekfrrenglsvtpeetivtvggsqalfnlfqaildpgdeviv
    lspywvsypemvrfaggvvvevetlpeegfvpdpervrraitprtkalvvnspnnptgav
    ypkevlealarlavehdfylvsdeiyehllyegehfspgrvapehtltvngaakafamtg
    wrigyacgpkevikamasvsrqsttspdtiaqwatlealtnqeasrafvemareayrrrr
    dlllegltalglkavrpsgafyvlmdtspiapdevraaerlleagvavvpgtdfaafghv
    rlsyatseenlrkalerfarvlgra
    

    Sequence, based on observed residues (ATOM records): (download)
    >1gc3G (G:)
    mrglsrrvqamkpdavvavnakalelrrqgvdlvaltagepdfdtpehvkeaarralaqg
    ktkyappagipelrealaekfrrenglsvtpeetivtvggsqalfnlfqaildpgdeviv
    lspywvsypemvrfaggvvvevetlpeegfvpdpervrraitprtkalvvnspnnptgav
    ypkevlealarlavehdfylvsdeiyehllyegehfspgrvapehtltvngaakafamtg
    wrigyacgpkevikamasvsrqsttspdtiaqwatlealtnqeasrafvemareayrrrr
    dlllegltalglkavrpsgafyvlmdtspiapdevraaerlleagvavvpgtdfaafghv
    rlsyatseenlrkalerfarvl
    

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >1gc3H (H:)
    mrglsrrvqamkpdavvavnakalelrrqgvdlvaltagepdfdtpehvkeaarralaqg
    ktkyappagipelrealaekfrrenglsvtpeetivtvggsqalfnlfqaildpgdeviv
    lspywvsypemvrfaggvvvevetlpeegfvpdpervrraitprtkalvvnspnnptgav
    ypkevlealarlavehdfylvsdeiyehllyegehfspgrvapehtltvngaakafamtg
    wrigyacgpkevikamasvsrqsttspdtiaqwatlealtnqeasrafvemareayrrrr
    dlllegltalglkavrpsgafyvlmdtspiapdevraaerlleagvavvpgtdfaafghv
    rlsyatseenlrkalerfarvlgra
    

    Sequence, based on observed residues (ATOM records): (download)
    >1gc3H (H:)
    mrglsrrvqamkpdavvavnakalelrrqgvdlvaltagepdfdtpehvkeaarralaqg
    ktkyappagipelrealaekfrrenglsvtpeetivtvggsqalfnlfqaildpgdeviv
    lspywvsypemvrfaggvvvevetlpeegfvpdpervrraitprtkalvvnspnnptgav
    ypkevlealarlavehdfylvsdeiyehllyegehfspgrvapehtltvngaakafamtg
    wrigyacgpkevikamasvsrqsttspdtiaqwatlealtnqeasrafvemareayrrrr
    dlllegltalglkavrpsgafyvlmdtspiapdevraaerlleagvavvpgtdfaafghv
    rlsyatseenlrkalerfarvl