PDB entry 1gbb

View 1gbb on RCSB PDB site
Description: Alpha-lytic protease with met 190 replaced by ALA AND GLY 216 replaced by ALA complex with METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID
Class: hydrolase/hydrolase inhibitor
Keywords: active-site mutation, serine proteinase, hydrolase-hydrolase inhibitor complex
Deposited on 1995-09-06, released 1996-01-29
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: 0.142
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: alpha-lytic protease
    Species: Lysobacter enzymogenes [TaxId:69]
    Gene: ALPHA-LYTIC PROTEASE PREPROENZ
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00778 (Start-197)
      • engineered mutation (137)
      • engineered mutation (160)
    Domains in SCOPe 2.07: d1gbba_
  • Chain 'P':
    Compound: methoxysuccinyl-ala-ala-pro-alanine boronic acid inhibitor
    Database cross-references and differences (RAF-indexed):
    • PDB 1GBB (4-End)
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1gbbA (A:)
anivggieysinnaslcsvgfsvtrgatkgfvtaghcgtvnatariggavvgtfaarvfp
gndrawvsltsaqtllprvangssfvtvrgsteaavgaavcrsgrttgyqcgtitaknvt
anyaegavrgltqgnacagrgdsggswitsagqaqgvmsganvqsngnncgipasqrssl
ferlqpilsqyglslvtg

  • Chain 'P':
    No sequence available.