PDB entry 1g73

View 1g73 on RCSB PDB site
Description: crystal structure of smac bound to xiap-bir3 domain
Class: apoptosis/apoptosis inhibitor
Keywords: helix bundle, zinc-binding domain, APOPTOSIS/APOPTOSIS INHIBITOR COMPLEX
Deposited on 2000-11-08, released 2001-01-10
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.227
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: second mitochondria-derived activator of caspases
    Species: Homo sapiens [TaxId:9606]
    Gene: SMAC
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NR28 (0-End)
      • engineered (32)
    Domains in SCOPe 2.06: d1g73a_
  • Chain 'B':
    Compound: second mitochondria-derived activator of caspases
    Species: Homo sapiens [TaxId:9606]
    Gene: SMAC
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NR28 (0-End)
      • engineered (32)
    Domains in SCOPe 2.06: d1g73b_
  • Chain 'C':
    Compound: inhibitors of apoptosis-like protein ilp
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1g73c_
  • Chain 'D':
    Compound: inhibitors of apoptosis-like protein ilp
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1g73d_
  • Heterogens: ZN

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1g73A (A:)
avpiaqksephslssealmrravslvtdststdlsqttyalieaiteytkavytltslyr
qytsllgkmnseeedevwqviigaraemtskhqeylklettwmtavglsemaaeaayqtg
adqasitarnhiqlvklqveevhqlsrkaetklaeaqieelr

    Sequence, based on observed residues (ATOM records): (download) 
    >1g73A (A:)
avpiaqksephslssealmrravslvtdststdlsqttyalieaiteytkavytltslyr
qytsllgkmnseeedevwqviigaraemtskhqeylklettwmtavglsemaaeaayqtg
adqasitarnhiqlvklqveevhqlsrkaetklaeaq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1g73B (B:)
avpiaqksephslssealmrravslvtdststdlsqttyalieaiteytkavytltslyr
qytsllgkmnseeedevwqviigaraemtskhqeylklettwmtavglsemaaeaayqtg
adqasitarnhiqlvklqveevhqlsrkaetklaeaqieelr

    Sequence, based on observed residues (ATOM records): (download) 
    >1g73B (B:)
avpiaqksephslssealmrravslvtdststdlsqttyalieaiteytkavytltslyr
qytsllgkmnseeedevwqviigaraemtskhqeylklettwmtavglsemaaeaayqtg
adqasitarnhiqlvklqveevhqlsrkaetklaeaq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1g73C (C:)
rsesdavssdrnfpnstnlprnpsmadyeariftfgtwiysvnkeqlaragfyalgegdk
vkcfhcgggltdwkpsedpweqhakwypgckylleqkgqeyinnihlthsleeclvrtte
k

    Sequence, based on observed residues (ATOM records): (download) 
    >1g73C (C:)
lprnpsmadyeariftfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwkpsed
pweqhakwypgckylleqkgqeyinnihl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1g73D (D:)
rsesdavssdrnfpnstnlprnpsmadyeariftfgtwiysvnkeqlaragfyalgegdk
vkcfhcgggltdwkpsedpweqhakwypgckylleqkgqeyinnihlthsleeclvrtte
k

    Sequence, based on observed residues (ATOM records): (download) 
    >1g73D (D:)
lprnpsmadyeariftfgtwiysvnkeqlaragfyalgegdkvkcfhcgggltdwkpsed
pweqhakwypgckylleqkgqeyinnihlthsleeclvrtte