PDB entry 1g49

View 1g49 on RCSB PDB site
Description: a carboxylic acid based inhibitor in complex with mmp3
Class: hydrolase
Keywords: mixed alpha beta structure, Zinc protease, inhibited, hydrolase
Deposited on 2000-10-26, released 2001-10-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-04, with a file datestamp of 2017-09-29.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: matrix metalloproteinase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: MMP3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1g49a_
  • Chain 'B':
    Compound: matrix metalloproteinase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: MMP3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1g49b_
  • Heterogens: ZN, CA, 111, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1g49A (A:)
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misfavrehgdfypfdgpgnvlahayapgpgingdahfdddeqwtkdttgtnlflvaahe
ighslglfhsantealmyplyhsltdltrfrlsqddingiqslygpppdspet

    Sequence, based on observed residues (ATOM records): (download) 
    >1g49A (A:)
frtfpgipkwrkthltyrivnytpdlpkdavdsavekalkvweevtpltfsrlyegeadi
misfavrehgdfypfdgpgnvlahayapgpgingdahfdddeqwtkdttgtnlflvaahe
ighslglfhsantealmyplyhsltdltrfrlsqddingiqslygpppd

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1g49B (B:)
frtfpgipkwrkthltyrivnytpdlpkdavdsavekalkvweevtpltfsrlyegeadi
misfavrehgdfypfdgpgnvlahayapgpgingdahfdddeqwtkdttgtnlflvaahe
ighslglfhsantealmyplyhsltdltrfrlsqddingiqslygpppdspet