PDB entry 1g23

View 1g23 on RCSB PDB site
Description: the structural basis of the catalytic mechanism and regulation of glucose-1-phosphate thymidylyltransferase (rmla). glucose-1-phosphate complex.
Class: transferase
Keywords: L-rhamnose, nucleotidyltransferase, pyrophosphorylase, thymidylyltransferase, allostery, TRANSFERASE
Deposited on 2000-10-16, released 2000-12-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glucose-1-phosphate thymidylyltransferase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HU22 (Start-292)
      • modified residue (34)
      • modified residue (43)
      • modified residue (216)
    Domains in SCOPe 2.08: d1g23a_
  • Chain 'B':
    Compound: glucose-1-phosphate thymidylyltransferase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HU22 (Start-292)
      • modified residue (34)
      • modified residue (43)
      • modified residue (216)
    Domains in SCOPe 2.08: d1g23b_
  • Chain 'C':
    Compound: glucose-1-phosphate thymidylyltransferase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HU22 (Start-292)
      • modified residue (34)
      • modified residue (43)
      • modified residue (216)
    Domains in SCOPe 2.08: d1g23c_
  • Chain 'D':
    Compound: glucose-1-phosphate thymidylyltransferase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HU22 (Start-292)
      • modified residue (34)
      • modified residue (43)
      • modified residue (216)
    Domains in SCOPe 2.08: d1g23d_
  • Chain 'E':
    Compound: glucose-1-phosphate thymidylyltransferase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HU22 (Start-292)
      • modified residue (34)
      • modified residue (43)
      • modified residue (216)
    Domains in SCOPe 2.08: d1g23e_
  • Chain 'F':
    Compound: glucose-1-phosphate thymidylyltransferase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HU22 (Start-292)
      • modified residue (34)
      • modified residue (43)
      • modified residue (216)
    Domains in SCOPe 2.08: d1g23f_
  • Chain 'G':
    Compound: glucose-1-phosphate thymidylyltransferase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HU22 (Start-292)
      • modified residue (34)
      • modified residue (43)
      • modified residue (216)
    Domains in SCOPe 2.08: d1g23g_
  • Chain 'H':
    Compound: glucose-1-phosphate thymidylyltransferase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HU22 (Start-292)
      • modified residue (34)
      • modified residue (43)
      • modified residue (216)
    Domains in SCOPe 2.08: d1g23h_
  • Heterogens: G1P, SO4

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1g23A (A:)
    mkrkgiilaggsgtrlhpatlaiskqllpvydkpmiyyplstlmlagireiliistpqdt
    prfqqllgdgsnwgldlqyavqpspdglaqafligesfigndlsalvlgdnlyyghdfhe
    llgsasqrqtgasvfayhvldperygvvefdqggkaisleekplepksnyavtglyfydq
    qvvdiardlkpsprgeleitdvnraylergqlsveimgrgyawldtgthdslleagqfia
    tlenrqglkvacpeeiayrqkwidaaqleklaaplakngygqylkrlltetvy
    

    Sequence, based on observed residues (ATOM records): (download)
    >1g23A (A:)
    krkgiilaggsgtrlhpatlaiskqllpvydkpmiyyplstlmlagireiliistpqdtp
    rfqqllgdgsnwgldlqyavqpspdglaqafligesfigndlsalvlgdnlyyghdfhel
    lgsasqrqtgasvfayhvldperygvvefdqggkaisleekplepksnyavtglyfydqq
    vvdiardlkpsprgeleitdvnraylergqlsveimgrgyawldtgthdslleagqfiat
    lenrqglkvacpeeiayrqkwidaaqleklaaplakngygqylkrlltetvy
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1g23B (B:)
    mkrkgiilaggsgtrlhpatlaiskqllpvydkpmiyyplstlmlagireiliistpqdt
    prfqqllgdgsnwgldlqyavqpspdglaqafligesfigndlsalvlgdnlyyghdfhe
    llgsasqrqtgasvfayhvldperygvvefdqggkaisleekplepksnyavtglyfydq
    qvvdiardlkpsprgeleitdvnraylergqlsveimgrgyawldtgthdslleagqfia
    tlenrqglkvacpeeiayrqkwidaaqleklaaplakngygqylkrlltetvy
    

    Sequence, based on observed residues (ATOM records): (download)
    >1g23B (B:)
    krkgiilaggsgtrlhpatlaiskqllpvydkpmiyyplstlmlagireiliistpqdtp
    rfqqllgdgsnwgldlqyavqpspdglaqafligesfigndlsalvlgdnlyyghdfhel
    lgsasqrqtgasvfayhvldperygvvefdqggkaisleekplepksnyavtglyfydqq
    vvdiardlkpsprgeleitdvnraylergqlsveimgrgyawldtgthdslleagqfiat
    lenrqglkvacpeeiayrqkwidaaqleklaaplakngygqylkrlltetvy
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >1g23C (C:)
    mkrkgiilaggsgtrlhpatlaiskqllpvydkpmiyyplstlmlagireiliistpqdt
    prfqqllgdgsnwgldlqyavqpspdglaqafligesfigndlsalvlgdnlyyghdfhe
    llgsasqrqtgasvfayhvldperygvvefdqggkaisleekplepksnyavtglyfydq
    qvvdiardlkpsprgeleitdvnraylergqlsveimgrgyawldtgthdslleagqfia
    tlenrqglkvacpeeiayrqkwidaaqleklaaplakngygqylkrlltetvy
    

    Sequence, based on observed residues (ATOM records): (download)
    >1g23C (C:)
    krkgiilaggsgtrlhpatlaiskqllpvydkpmiyyplstlmlagireiliistpqdtp
    rfqqllgdgsnwgldlqyavqpspdglaqafligesfigndlsalvlgdnlyyghdfhel
    lgsasqrqtgasvfayhvldperygvvefdqggkaisleekplepksnyavtglyfydqq
    vvdiardlkpsprgeleitdvnraylergqlsveimgrgyawldtgthdslleagqfiat
    lenrqglkvacpeeiayrqkwidaaqleklaaplakngygqylkrlltetvy
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1g23D (D:)
    mkrkgiilaggsgtrlhpatlaiskqllpvydkpmiyyplstlmlagireiliistpqdt
    prfqqllgdgsnwgldlqyavqpspdglaqafligesfigndlsalvlgdnlyyghdfhe
    llgsasqrqtgasvfayhvldperygvvefdqggkaisleekplepksnyavtglyfydq
    qvvdiardlkpsprgeleitdvnraylergqlsveimgrgyawldtgthdslleagqfia
    tlenrqglkvacpeeiayrqkwidaaqleklaaplakngygqylkrlltetvy
    

    Sequence, based on observed residues (ATOM records): (download)
    >1g23D (D:)
    krkgiilaggsgtrlhpatlaiskqllpvydkpmiyyplstlmlagireiliistpqdtp
    rfqqllgdgsnwgldlqyavqpspdglaqafligesfigndlsalvlgdnlyyghdfhel
    lgsasqrqtgasvfayhvldperygvvefdqggkaisleekplepksnyavtglyfydqq
    vvdiardlkpsprgeleitdvnraylergqlsveimgrgyawldtgthdslleagqfiat
    lenrqglkvacpeeiayrqkwidaaqleklaaplakngygqylkrlltetvy
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >1g23E (E:)
    mkrkgiilaggsgtrlhpatlaiskqllpvydkpmiyyplstlmlagireiliistpqdt
    prfqqllgdgsnwgldlqyavqpspdglaqafligesfigndlsalvlgdnlyyghdfhe
    llgsasqrqtgasvfayhvldperygvvefdqggkaisleekplepksnyavtglyfydq
    qvvdiardlkpsprgeleitdvnraylergqlsveimgrgyawldtgthdslleagqfia
    tlenrqglkvacpeeiayrqkwidaaqleklaaplakngygqylkrlltetvy
    

    Sequence, based on observed residues (ATOM records): (download)
    >1g23E (E:)
    krkgiilaggsgtrlhpatlaiskqllpvydkpmiyyplstlmlagireiliistpqdtp
    rfqqllgdgsnwgldlqyavqpspdglaqafligesfigndlsalvlgdnlyyghdfhel
    lgsasqrqtgasvfayhvldperygvvefdqggkaisleekplepksnyavtglyfydqq
    vvdiardlkpsprgeleitdvnraylergqlsveimgrgyawldtgthdslleagqfiat
    lenrqglkvacpeeiayrqkwidaaqleklaaplakngygqylkrlltetvy
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >1g23F (F:)
    mkrkgiilaggsgtrlhpatlaiskqllpvydkpmiyyplstlmlagireiliistpqdt
    prfqqllgdgsnwgldlqyavqpspdglaqafligesfigndlsalvlgdnlyyghdfhe
    llgsasqrqtgasvfayhvldperygvvefdqggkaisleekplepksnyavtglyfydq
    qvvdiardlkpsprgeleitdvnraylergqlsveimgrgyawldtgthdslleagqfia
    tlenrqglkvacpeeiayrqkwidaaqleklaaplakngygqylkrlltetvy
    

    Sequence, based on observed residues (ATOM records): (download)
    >1g23F (F:)
    krkgiilaggsgtrlhpatlaiskqllpvydkpmiyyplstlmlagireiliistpqdtp
    rfqqllgdgsnwgldlqyavqpspdglaqafligesfigndlsalvlgdnlyyghdfhel
    lgsasqrqtgasvfayhvldperygvvefdqggkaisleekplepksnyavtglyfydqq
    vvdiardlkpsprgeleitdvnraylergqlsveimgrgyawldtgthdslleagqfiat
    lenrqglkvacpeeiayrqkwidaaqleklaaplakngygqylkrlltetvy
    

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >1g23G (G:)
    mkrkgiilaggsgtrlhpatlaiskqllpvydkpmiyyplstlmlagireiliistpqdt
    prfqqllgdgsnwgldlqyavqpspdglaqafligesfigndlsalvlgdnlyyghdfhe
    llgsasqrqtgasvfayhvldperygvvefdqggkaisleekplepksnyavtglyfydq
    qvvdiardlkpsprgeleitdvnraylergqlsveimgrgyawldtgthdslleagqfia
    tlenrqglkvacpeeiayrqkwidaaqleklaaplakngygqylkrlltetvy
    

    Sequence, based on observed residues (ATOM records): (download)
    >1g23G (G:)
    krkgiilaggsgtrlhpatlaiskqllpvydkpmiyyplstlmlagireiliistpqdtp
    rfqqllgdgsnwgldlqyavqpspdglaqafligesfigndlsalvlgdnlyyghdfhel
    lgsasqrqtgasvfayhvldperygvvefdqggkaisleekplepksnyavtglyfydqq
    vvdiardlkpsprgeleitdvnraylergqlsveimgrgyawldtgthdslleagqfiat
    lenrqglkvacpeeiayrqkwidaaqleklaaplakngygqylkrlltetvy
    

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >1g23H (H:)
    mkrkgiilaggsgtrlhpatlaiskqllpvydkpmiyyplstlmlagireiliistpqdt
    prfqqllgdgsnwgldlqyavqpspdglaqafligesfigndlsalvlgdnlyyghdfhe
    llgsasqrqtgasvfayhvldperygvvefdqggkaisleekplepksnyavtglyfydq
    qvvdiardlkpsprgeleitdvnraylergqlsveimgrgyawldtgthdslleagqfia
    tlenrqglkvacpeeiayrqkwidaaqleklaaplakngygqylkrlltetvy
    

    Sequence, based on observed residues (ATOM records): (download)
    >1g23H (H:)
    krkgiilaggsgtrlhpatlaiskqllpvydkpmiyyplstlmlagireiliistpqdtp
    rfqqllgdgsnwgldlqyavqpspdglaqafligesfigndlsalvlgdnlyyghdfhel
    lgsasqrqtgasvfayhvldperygvvefdqggkaisleekplepksnyavtglyfydqq
    vvdiardlkpsprgeleitdvnraylergqlsveimgrgyawldtgthdslleagqfiat
    lenrqglkvacpeeiayrqkwidaaqleklaaplakngygqylkrlltetvy