PDB entry 1fvt

View 1fvt on RCSB PDB site
Description: the structure of cyclin-dependent kinase 2 (cdk2) in complex with an oxindole inhibitor
Class: transferase, cell cycle
Keywords: cyclin-dependent kinase, oxindole, TRANSFERASE, CELL CYCLE
Deposited on 2000-09-20, released 2001-01-17
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-04, with a file datestamp of 2017-09-29.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1fvta_
  • Heterogens: 106, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1fvtA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >1fvtA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirvpstaireisllkelnhpnivkll
    dvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrd
    lkpqnllintegaikladfglarafgvvtlwyrapeillgckyystavdiwslgcifaem
    vtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppld
    edgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl