PDB entry 1ft8

View 1ft8 on RCSB PDB site
Description: crystal structure of the RNA-binding domain of the mRNA export factor tap
Class: RNA binding protein
Keywords: ribonucleoprotein (RNP, RRM, RBD) and leucine-rich-repeat (LRR) domains, RNA BINDING PROTEIN
Deposited on 2000-09-12, released 2000-12-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 3.15 Å
R-factor: 0.303
AEROSPACI score: -1.87 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tip associating protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UBU9
      • engineered (17)
      • engineered (124)
    Domains in SCOPe 2.08: d1ft8a1, d1ft8a2
  • Chain 'B':
    Compound: tip associating protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UBU9
      • engineered (124)
    Domains in SCOPe 2.08: d1ft8b_
  • Chain 'C':
    Compound: tip associating protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UBU9
      • engineered (17)
      • engineered (124)
    Domains in SCOPe 2.08: d1ft8c1, d1ft8c2
  • Chain 'D':
    Compound: tip associating protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UBU9
      • engineered (124)
    Domains in SCOPe 2.08: d1ft8d_
  • Chain 'E':
    Compound: tip associating protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UBU9
      • engineered (17)
    Domains in SCOPe 2.08: d1ft8e_

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1ft8A (A:)
    pperggagtsqdgtsknwfkitipygrkydkawllsmiqskcsvpftpiefhyentraqf
    fvedastasalkavnykildrenrrisiiinssapphtilnelkpeqveqlklimskryd
    gsqqvldlkglrsdpdlvaqnidvvlnrrscmaatlriieenipellslnlsnnrlyrld
    dmssivqkapnlkilnlsgnelksereldkikglkleelwldgnslcdtfrdqstyisai
    rerfpkllrldghelpppiafdveapttlpp
    

    Sequence, based on observed residues (ATOM records): (download)
    >1ft8A (A:)
    nwfkitipygrkydkawllsmiqskcsvpftpiefhyentraqffvedastasalkavny
    kildrenrrisiiinssapphtelkpeqveqlklimskrydgsqqvldlkglrsdpdlva
    qnidvvlnrrscmaatlriieenipellslnlsnnrlyrlddmssivqkapnlkilnlsg
    nelksereldkikglkleelwldgnslcdtfrdqstyisairerfpkllrldghelpppi
    af
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1ft8B (B:)
    pperggagtsqdgtsknwfkitipygrkydkawllsmiqskcsvpftpiefhyentraqf
    fvedastasalkavnykildrenrrisiiinssapphtilnelkpeqveqlklimskryd
    gsqqvldlkglrsdpdlvaqnidvvlnrrscmaatlriieenipellslnlsnnrlyrld
    dmssivqkapnlkilnlsgnelksereldkikglkleelwldgnslcdtfrdqstyisai
    rerfpkllrldghelpppiafdveapttlpp
    

    Sequence, based on observed residues (ATOM records): (download)
    >1ft8B (B:)
    elkpeqveqlklimskrydgsqqvldlkglrsdpdlvaqnidvvlnrrscmaatlriiee
    nipellslnlsnnrlyrlddmssivqkapnlkilnlsgnelksereldkikglkleelwl
    dgnslcdtfrdqstyisairerfpkllrldghelpppiafdveap
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >1ft8C (C:)
    pperggagtsqdgtsknwfkitipygrkydkawllsmiqskcsvpftpiefhyentraqf
    fvedastasalkavnykildrenrrisiiinssapphtilnelkpeqveqlklimskryd
    gsqqvldlkglrsdpdlvaqnidvvlnrrscmaatlriieenipellslnlsnnrlyrld
    dmssivqkapnlkilnlsgnelksereldkikglkleelwldgnslcdtfrdqstyisai
    rerfpkllrldghelpppiafdveapttlpp
    

    Sequence, based on observed residues (ATOM records): (download)
    >1ft8C (C:)
    knwfkitipygrkydkawllsmiqskcsvpftpiefhyentraqffvedastasalkavn
    ykildrenrrisiiinssapphlnelkpeqveqlklimskrydgsqqvldlkglrsdpdl
    vaqnidvvlnrrscmaatlriieenipellslnlsnnrlyrlddmssivqkapnlkilnl
    sgnelksereldkikglkleelwldgnslcdtfrdqstyisairerfpkllrldghelpp
    piaf
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1ft8D (D:)
    pperggagtsqdgtsknwfkitipygrkydkawllsmiqskcsvpftpiefhyentraqf
    fvedastasalkavnykildrenrrisiiinssapphtilnelkpeqveqlklimskryd
    gsqqvldlkglrsdpdlvaqnidvvlnrrscmaatlriieenipellslnlsnnrlyrld
    dmssivqkapnlkilnlsgnelksereldkikglkleelwldgnslcdtfrdqstyisai
    rerfpkllrldghelpppiafdveapttlpp
    

    Sequence, based on observed residues (ATOM records): (download)
    >1ft8D (D:)
    lkpeqveqlklimskrydgsqqvldlkglrsdpdlvaqnidvvlnrrscmaatlriieen
    ipellslnlsnnrlyrlddmssivqkapnlkilnlsgnelksereldkikglkleelwld
    gnslcdtfrdqstyisairerfpkllrldghelpppiafdve
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >1ft8E (E:)
    pperggagtsqdgtsknwfkitipygrkydkawllsmiqskcsvpftpiefhyentraqf
    fvedastasalkavnykildrenrrisiiinssapphtilnelkpeqveqlklimskryd
    gsqqvldlkglrsdpdlvaqnidvvlnrrscmaatlriieenipellslnlsnnrlyrld
    dmssivqkapnlkilnlsgnelksereldkikglkleelwldgnslcdtfrdqstyisai
    rerfpkllrldghelpppiafdveapttlpp
    

    Sequence, based on observed residues (ATOM records): (download)
    >1ft8E (E:)
    wfkitdkawllsmiqskcsvpftpiefhqffvedastasalkav