PDB entry 1fst

View 1fst on RCSB PDB site
Description: crystal structure of truncated human rhogdi triple mutant
Class: signaling protein inhibitor
Keywords: immunoglobulin fold, beta sandwich motif, isoprenyl-binding domain, GDP-dissociation inhibitor of Rho GTPases, SIGNALING PROTEIN INHIBITOR
Deposited on 2000-09-11, released 2001-05-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.213
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: rho GDP-dissociation inhibitor 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P52565
      • engineered (112)
      • engineered (115)
      • engineered (118)
    Domains in SCOPe 2.08: d1fsta_
  • Chain 'B':
    Compound: rho GDP-dissociation inhibitor 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P52565
      • engineered (112)
      • engineered (115)
      • engineered (118)
    Domains in SCOPe 2.08: d1fstb_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1fstA (A:)
msvnykppaqksiqeiqeldkddeslrkykeallgrvavsadpnvpnvvvtgltlvcssa
pgpleldltgdlesfkkqsfvlkegveyrikisfrvnreivsgmkyiqhtyragvaidat
dymvgsygpraeeyefltpveeapkgmlargsysiksrftdddktdhlswewnltikkdw
kd

    Sequence, based on observed residues (ATOM records): (download) 
    >1fstA (A:)
nvpnvvvtgltlvcssapgpleldltgdlesfkkqsfvlkegveyrikisfrvnreivsg
mkyiqhtyragvaidatdymvgsygpraeeyefltpveeapkgmlargsysiksrftddd
ktdhlswewnltikkdwk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1fstB (B:)
msvnykppaqksiqeiqeldkddeslrkykeallgrvavsadpnvpnvvvtgltlvcssa
pgpleldltgdlesfkkqsfvlkegveyrikisfrvnreivsgmkyiqhtyragvaidat
dymvgsygpraeeyefltpveeapkgmlargsysiksrftdddktdhlswewnltikkdw
kd

    Sequence, based on observed residues (ATOM records): (download) 
    >1fstB (B:)
lgrvavsadpnvpnvvvtgltlvcssapgpleldltgdlesfkkqsfvlkegveyrikis
frvnreivsgmkyiqhtyragvaidatdymvgsygpraeeyefltpveeapkgmlargsy
siksrftdddktdhlswewnltikkdwk