PDB entry 1fs1

View 1fs1 on RCSB PDB site
Description: insights into scf ubiquitin ligases from the structure of the skp1-skp2 complex
Class: ligase
Keywords: Skp1, Skp2, F-box, LRR, leucine-rich repeat, SCF, ubiquitin, E3, ubiquitin protein ligase
Deposited on 2000-09-08, released 2000-11-29
The last revision prior to the SCOP 1.75 freeze date was dated 2003-04-01, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.218
AEROSPACI score: 0.58 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cyclin a/cdk2-associated p19
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1fs1a1
  • Chain 'B':
    Compound: cyclin a/cdk2-associated p45
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1fs1b1, d1fs1b2
  • Chain 'C':
    Compound: cyclin a/cdk2-associated p19
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1fs1c1
  • Chain 'D':
    Compound: cyclin a/cdk2-associated p45
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1fs1d1, d1fs1d2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1fs1A (A:)
renfpgvswdslpdelllgifsclclpellkvsgvckrwyrlasdeslwqtld

    Sequence, based on observed residues (ATOM records): (download) 
    >1fs1A (A:)
wdslpdelllgifsclclpellkvsgvckrwyrlasdeslw

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1fs1B (B:)
mpsiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhk
ddppppeddenkekrtddipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanm
ikgktpeeirktfnikndfte

    Sequence, based on observed residues (ATOM records): (download) 
    >1fs1B (B:)
psiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhkd
dpvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpeeirktfn

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1fs1C (C:)
renfpgvswdslpdelllgifsclclpellkvsgvckrwyrlasdeslwqtld

    Sequence, based on observed residues (ATOM records): (download) 
    >1fs1C (C:)
wdslpdelllgifsclclpellkvsgvckrwyrlasdeslw

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1fs1D (D:)
mpsiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhk
ddppppeddenkekrtddipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanm
ikgktpeeirktfnikndfte

    Sequence, based on observed residues (ATOM records): (download) 
    >1fs1D (D:)
psiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhkd
ddipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpeeirktfn