PDB entry 1fro

View 1fro on RCSB PDB site
Description: human glyoxalase I with benzyl-glutathione inhibitor
Class: lactoylglutathione lyase
Keywords: lactoylglutathione lyase, glyoxalase I
Deposited on 1997-02-25, released 1997-06-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.211
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: lactoylglutathione lyase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1froa_
  • Chain 'B':
    Compound: lactoylglutathione lyase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1frob_
  • Chain 'C':
    Compound: lactoylglutathione lyase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1froc_
  • Chain 'D':
    Compound: lactoylglutathione lyase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1frod_
  • Heterogens: ZN, GSB, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1froA (A:)
aepqppsggltdeaalsccsdadpstkdfllqqtmlrvkdpkksldfytrvlgmtliqkc
dfpimkfslyflayedkndipkekdekiawalsrkatlelthnwgteddetqsyhngnsd
prgfghigiavpdvysackrfeelgvkfvkkpddgkmkglafiqdpdgywieilnpnkma
tlm

    Sequence, based on observed residues (ATOM records): (download) 
    >1froA (A:)
ggltdeaalsccsdadpstkdfllqqtmlrvkdpkksldfytrvlgmtliqkcdfpimkf
slyflayedkndipkekdekiawalsrkatlelthnwgteddetqsyhngnsdprgfghi
giavpdvysackrfeelgvkfvkkpddgkmkglafiqdpdgywieilnpnkmatlm

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1froB (B:)
aepqppsggltdeaalsccsdadpstkdfllqqtmlrvkdpkksldfytrvlgmtliqkc
dfpimkfslyflayedkndipkekdekiawalsrkatlelthnwgteddetqsyhngnsd
prgfghigiavpdvysackrfeelgvkfvkkpddgkmkglafiqdpdgywieilnpnkma
tlm

    Sequence, based on observed residues (ATOM records): (download) 
    >1froB (B:)
ggltdeaalsccsdadpstkdfllqqtmlrvkdpkksldfytrvlgmtliqkcdfpimkf
slyflayedkndipkekdekiawalsrkatlelthnwgteddetqsyhngnsdprgfghi
giavpdvysackrfeelgvkfvkkpddgkmkglafiqdpdgywieilnpnkmatlm

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1froC (C:)
aepqppsggltdeaalsccsdadpstkdfllqqtmlrvkdpkksldfytrvlgmtliqkc
dfpimkfslyflayedkndipkekdekiawalsrkatlelthnwgteddetqsyhngnsd
prgfghigiavpdvysackrfeelgvkfvkkpddgkmkglafiqdpdgywieilnpnkma
tlm

    Sequence, based on observed residues (ATOM records): (download) 
    >1froC (C:)
ggltdeaalsccsdadpstkdfllqqtmlrvkdpkksldfytrvlgmtliqkcdfpimkf
slyflayedkndipkekdekiawalsrkatlelthnwgteddetqsyhngnsdprgfghi
giavpdvysackrfeelgvkfvkkpddgkmkglafiqdpdgywieilnpnkmatlm

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1froD (D:)
aepqppsggltdeaalsccsdadpstkdfllqqtmlrvkdpkksldfytrvlgmtliqkc
dfpimkfslyflayedkndipkekdekiawalsrkatlelthnwgteddetqsyhngnsd
prgfghigiavpdvysackrfeelgvkfvkkpddgkmkglafiqdpdgywieilnpnkma
tlm

    Sequence, based on observed residues (ATOM records): (download) 
    >1froD (D:)
ggltdeaalsccsdadpstkdfllqqtmlrvkdpkksldfytrvlgmtliqkcdfpimkf
slyflayedkndipkekdekiawalsrkatlelthnwgteddetqsyhngnsdprgfghi
giavpdvysackrfeelgvkfvkkpddgkmkglafiqdpdgywieilnpnkmatlm