PDB entry 1fqx
View 1fqx on RCSB PDB site
Description: crystal structure of the complex of hiv-1 protease with a peptidomimetic inhibitor
Class: hydrolase
Keywords: aspartyl protease, protease, hiv, peptidomimetic, inhibitor, drug design, hydroxyethylamine isostere
Deposited on
2000-09-07, released
2001-03-14
The last revision prior to the SCOP 1.73 freeze date was dated
2001-03-14, with a file datestamp of
2007-06-04.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: 0.18
AEROSPACI score: 0.24
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: protease retropepsin
Species: Human immunodeficiency virus
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.73: d1fqxa_ - Chain 'B':
Compound: protease retropepsin
Species: Human immunodeficiency virus
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.73: d1fqxb_ - Chain 'I':
Compound: boc-phe-psi[(s)-ch(oh)ch2nh]-phe-glu-phe-nh2
- Heterogens: NH2, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1fqxA (A:)
pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>1fqxB (B:)
pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf
- Chain 'I':
No sequence available.