PDB entry 1fqj

View 1fqj on RCSB PDB site
Description: crystal structure of the heterotrimeric complex of the rgs domain of rgs9, the gamma subunit of phosphodiesterase and the gt/i1 chimera alpha subunit [(rgs9)-(pdegamma)-(gt/i1alpha)-(GDP)-(alf4-)-(mg2+)]
Class: signaling protein
Keywords: RGS9, transducin, effector, PDEgamma, G Protein, Phototransduction, rod, RGS, phosphodiesterase, GAP, SIGNALING PROTEIN
Deposited on 2000-09-05, released 2001-02-28
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.02 Å
R-factor: 0.233
AEROSPACI score: -1.6 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: chimera of guanine nucleotide-binding protein g(t), alpha-1 subunit and guanine nucleotide-binding protein g(I), alpha-1 subunit
    Species: Bos taurus, Rattus norvegicus [TaxId:9913,10116]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1fqja1, d1fqja2
  • Chain 'B':
    Compound: regulator of g-protein signaling 9
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1fqjb_
  • Chain 'C':
    Compound: retinal rod rhodopsin-sensitive cgmp 3',5'-cyclic phosphodiesterase gamma-subunit
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1fqjc_
  • Chain 'D':
    Compound: chimera of guanine nucleotide-binding protein g(t), alpha-1 subunit and guanine nucleotide-binding protein g(I), alpha-1 subunit
    Species: Bos taurus, Rattus norvegicus [TaxId:9913,10116]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1fqjd1, d1fqjd2
  • Chain 'E':
    Compound: regulator of g-protein signaling 9
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1fqje_
  • Heterogens: MG, ALF, GDP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1fqjA (A:)
dartvkllllgagesgkstivkqmkiihqdgysleeclefiaiiygntlqsilaivramt
tlniqygdsarqddarklmhmadtieegtmpkemsdiiqrlwkdsgiqacfdraseyqln
dsagyylsdlerlvtpgyvpteqdvlrsrvkttgiietqfsfkdlnfrmfdvggqrserk
kwihcfegvtaiifcvalsdydlvlaedeemnrmhesmklfdsicnnkwftdtsiilfln
kkdlfeekikksplticypeyagsntyeeagnyikvqflelnmrrdvkeiyshmtcatdt
qnvkfvfdavtdiiikenlkdcglf

    Sequence, based on observed residues (ATOM records): (download) 
    >1fqjA (A:)
rtvkllllgagesgkstivkqmkiihqdgysleeclefiaiiygntlqsilaivramttl
niqygdsarqddarklmhmadtieegtmpkemsdiiqrlwkdsgiqacfdraseyqlnds
agyylsdlerlvtpgyvpteqdvlrsrvkttgiietqfsfkdlnfrmfdvggqrserkkw
ihcfegvtaiifcvalsdydlvlaedeemnrmhesmklfdsicnnkwftdtsiilflnkk
dlfeekikksplticypeyagsntyeeagnyikvqflelnmrrdvkeiyshmtcatdtqn
vkfvfdavtdiiikenl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1fqjB (B:)
qfwdlnaklvdiptkmrverwafnfselirdpkgrqsfqhflrkefsgenlgfweacedl
kygdqskvkekaeeiyklflapgarrwinidgktmditvkglkhphryvldaaqthiyml
mkkdsyarylkspiykemlakaiepqg

    Sequence, based on observed residues (ATOM records): (download) 
    >1fqjB (B:)
diptkmrverwafnfselirdpkgrqsfqhflrkefsgenlgfweacedlkygdqskvke
kaeeiyklflapgarrwinidgktmditvkglkhphryvldaaqthiymlmkkdsyaryl
kspiykemlakai

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1fqjC (C:)
gvqgfgddipgmeglgtditvicpweafnhlelhelaqygii

    Sequence, based on observed residues (ATOM records): (download) 
    >1fqjC (C:)
fgddipgmeglgtditvicpweafnhlelhelaqygii

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1fqjD (D:)
dartvkllllgagesgkstivkqmkiihqdgysleeclefiaiiygntlqsilaivramt
tlniqygdsarqddarklmhmadtieegtmpkemsdiiqrlwkdsgiqacfdraseyqln
dsagyylsdlerlvtpgyvpteqdvlrsrvkttgiietqfsfkdlnfrmfdvggqrserk
kwihcfegvtaiifcvalsdydlvlaedeemnrmhesmklfdsicnnkwftdtsiilfln
kkdlfeekikksplticypeyagsntyeeagnyikvqflelnmrrdvkeiyshmtcatdt
qnvkfvfdavtdiiikenlkdcglf

    Sequence, based on observed residues (ATOM records): (download) 
    >1fqjD (D:)
rtvkllllgagesgkstivkqmkiihqdgysleeclefiaiiygntlqsilaivramttl
niqygdsarqddarklmhmadtieegtmpkemsdiiqrlwkdsgiqacfdraseyqlnds
agyylsdlerlvtpgyvpteqdvlrsrvkttgiietqfsfkdlnfrmfdvggqrserkkw
ihcfegvtaiifcvalsdydlvlaedeemnrmhesmklfdsicnnkwftdtsiilflnkk
dlfeekikksplticypeyagsntyeeagnyikvqflelnmrrdvkeiyshmtcatdtqn
vkfvfdavtdiiike

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1fqjE (E:)
qfwdlnaklvdiptkmrverwafnfselirdpkgrqsfqhflrkefsgenlgfweacedl
kygdqskvkekaeeiyklflapgarrwinidgktmditvkglkhphryvldaaqthiyml
mkkdsyarylkspiykemlakaiepqg

    Sequence, based on observed residues (ATOM records): (download) 
    >1fqjE (E:)
fwdlnaklvdiptkmrverwafnfselirdpkgrqsfqhflrkefsgenlgfweacedlk
ygdqskvkekaeeiyklflapgarrwinidgktmditvkglkhphryvldaaqthiymlm
kkdsyarylkspiykemlaka