PDB entry 1fn7

View 1fn7 on RCSB PDB site
Description: coupling of damage recognition and catalysis by a human base-excision DNA repair protein
Class: hydrolase/DNA
Keywords: DNA REPAIR, DNA GLYCOSYLASE, PROTEIN/DNA, Helix hairpin helix, base recognition, oxoguanine, hydroxyguanine, base flipping, flipped-out base, extrahelical DNA, mechanism-based inhibitor, base-exicision repair, AP lyase, DNA glycosidase, HYDROLASE/DNA COMPLEX
Deposited on 2000-08-21, released 2001-04-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.221
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 8-oxoguanine DNA glycosylase 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15527 (0-316)
      • conflict (0-2)
    Domains in SCOPe 2.08: d1fn7a1, d1fn7a2
  • Chain 'C':
    Compound: DNA (5'-d(*gp*gp*tp*ap*gp*ap*cp*cp*tp*gp*gp*ap*cp*gp*c)-3')
  • Chain 'D':
    Compound: DNA (5'-d(*gp*cp*gp*tp*cp*cp*ap*(3dr)p*gp*tp*cp*tp*ap*cp*c)-3')
  • Heterogens: CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1fn7A (A:)
gseghrtlastpalwasipcprselrldlvlpsgqsfrwreqspahwsgvladqvwtltq
teeqlhctvyrgdksqasrptpdeleavrkyfqldvtlaqlyhhwgsvdshfqevaqkfq
gvrllrqdpieclfsficssnnniaritgmverlcqafgprliqlddvtyhgfpslqala
gpeveahlrklglgyraryvsasaraileeqgglawlqqlressyeeahkalcilpgvgt
kvadciclmaldkpqavpvdvhmwhiaqrdyswhpttsqakgpspqtnkelgnffrslwg
pyagwaqavlfsadlrq

    Sequence, based on observed residues (ATOM records): (download) 
    >1fn7A (A:)
gseghrtlastpalwasipcprselrldlvlpsgqsfrwreqspahwsgvladqvwtltq
teeqlhctvyrsqasrptpdeleavrkyfqldvtlaqlyhhwgsvdshfqevaqkfqgvr
llrqdpieclfsficssnnniaritgmverlcqafgprliqlddvtyhgfpslqalagpe
veahlrklglgyraryvsasaraileeqgglawlqqlressyeeahkalcilpgvgtkva
dciclmaldkpqavpvdvhmwhiaqrdyswhpttsqakgpspqtnkelgnffrslwgpya
gwaqavlfsadlrq

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.