PDB entry 1fm2

View 1fm2 on RCSB PDB site
Description: the 2 angstrom crystal structure of cephalosporin acylase
Class: hydrolase
Keywords: cephalosporin acylase, antibiotics, penicillin acylase, N-terminal hydrolase, HYDROLASE
Deposited on 2000-08-15, released 2001-08-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-31, with a file datestamp of 2018-01-26.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glutaryl 7-aminocephalosporanic acid acylase
    Species: Brevundimonas diminuta [TaxId:293]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9L5D6
      • modified residue (144)
    Domains in SCOPe 2.08: d1fm2.1
  • Chain 'B':
    Compound: glutaryl 7-aminocephalosporanic acid acylase
    Species: Brevundimonas diminuta [TaxId:293]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9L5D6 (0-519)
      • modified residue (63)
      • modified residue (72)
      • modified residue (148)
      • modified residue (155)
      • modified residue (168)
      • modified residue (171)
      • see remark 999 (256)
      • see remark 999 (258-259)
      • modified residue (281)
      • modified residue (293)
      • modified residue (303)
      • see remark 999 (336)
      • modified residue (415)
      • modified residue (459)
      • modified residue (472)
    Domains in SCOPe 2.08: d1fm2.1
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1fm2A (A:)
eptstpqapiaaykprsneilwdgygvphiygvdapsafygygwaqarshgdnilrlyge
argkgaeywgpdyeqttvwlltngvperaqqwyaqqspdfranldafaaginayaqqnpd
dispevrqvlpvsgadvvahahrlmnflyvaspgrtlgegdppdladqg

    Sequence, based on observed residues (ATOM records): (download) 
    >1fm2A (A:)
qapiaaykprsneilwdgygvphiygvdapsafygygwaqarshgdnilrlygeargkga
eywgpdyeqttvwlltngvperaqqwyaqqspdfranldafaaginayaqqnpddispev
rqvlpvsgadvvahahrlmnflyvaspgrtlg

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1fm2B (B:)
snswavapgktangnalllqnphlswttdyftyyeahlvtpdfeiygatqiglpvirfaf
nqrmgitntvngmvgatnyrltlqdggylydgqvrpferrqasyrlrqadgstvdkplei
rssvhgpvferadgtavavrvagldrpgmleqyfdmitahsfddyeaamarmqvptfniv
yadregtinysfngvapkraegdiafwqgnvpgdssrylwtethplddlprvtnppggfv
qnsndppwtptwpvtycpanhpsylapqtphslraqqsvrlmsenddltlerfmalqfsh
ravmadrtlpdlipaalidpdpevqaaarllaawdrdftsdsraallfeewarlfagqnf
agqaafatpwsldkpvstpygvrdpkaavdqlrtaiantkrkygaidrpfgdasrmilnd
vnvpgaagygnlgsfrvftwsdpdengirtpvhgetwvamiefstpvrayglmsygnsrq
pgtthysdqiervsradfrelllrreqveaavqertpfnf