PDB entry 1fit

View 1fit on RCSB PDB site
Description: fhit (fragile histidine triad protein)
Class: chromosomal translocation
Keywords: fhit, fragile histidine triad protein, putative human tumor suppressor, advanced photon source, aps, hit protein family, pkci, chromosomal translocation
Deposited on 1997-05-17, released 1997-11-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: fragile histidine protein
    Species: Homo sapiens [TaxId:9606]
    Gene: FHIT
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49789 (Start-146)
      • modified residue (81)
      • modified residue (134)
    Domains in SCOPe 2.08: d1fita_
  • Heterogens: FRU, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1fitA (A:)
msfrfgqhlikpsvvflktelsfalvnrkpvvpghvlvcplrpverfhdlrpdevadlfq
ttqrvgtvvekhfhgtsltfsmqdgpeagqtvkhvhvhvlprkagdfhrndsiyeelqkh
dkedfpaswrseeemaaeaaalrvyfq

    Sequence, based on observed residues (ATOM records): (download) 
    >1fitA (A:)
sfrfgqhlikpsvvflktelsfalvnrkpvvpghvlvcplrpverfhdlrpdevadlfqt
tqrvgtvvekhfhgtsltfsmqdgpeagqtvkhvhvhvlprkagdaswrseeemaaeaaa
lrvyfq