PDB entry 1fi4

View 1fi4 on RCSB PDB site
Description: the x-ray crystal structure of mevalonate 5-diphosphate decarboxylase at 2.3 angstrom resolution.
Class: lyase
Keywords: mixed alpha/beta structure, ATP binding, decarboxylase, cholesterol biosynthesis, structural genomics, PSI, Protein Structure Initiative, New York SGX Research Center for Structural Genomics, NYSGXRC, LYASE
Deposited on 2000-08-03, released 2001-03-21
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.27 Å
R-factor: 0.239
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: mevalonate 5-diphosphate decarboxylase
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P32377
      • modified residue (108)
      • modified residue (188)
      • modified residue (198)
      • modified residue (211)
      • modified residue (231)
      • modified residue (256)
      • modified residue (273-274)
      • modified residue (293)
    Domains in SCOPe 2.05: d1fi4a1, d1fi4a2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1fi4A (A:)
mgsshhhhhhssglvprgshmtvytasvtapvniatlkywgkrdtklnlptnssisvtls
qddlrtltsaatapeferdtlwlngephsidnertqnclrdlrqlrkemeskdaslptls
qwklhivsennfptaaglassaagfaalvsaiaklyqlpqstseisriarkgsgsacrsl
fggyvawemgkaedghdsmavqiadssdwpqmkacvlvvsdikkdvsstqgmqltvatse
lfkeriehvvpkrfevmrkaivekdfatfaketmmdsnsfhatcldsfppifymndtskr
iiswchtinqfygetivaytfdagpnavlyylaenesklfafiyklfgsvpgwdkkftte
qleafnhqfessnftareldlelqkdvarviltqvgsgpqetneslidaktglpke

    Sequence, based on observed residues (ATOM records): (download) 
    >1fi4A (A:)
vytasvtapvniatlkywgkrdtklnlptnssisvtlsqddlrtltsaatapeferdtlw
lngephsidnertqnclrdlrqlrkemeskdaslptlsqwklhivsennfptaaglassa
agfaalvsaiaklyqlpqstseisriarkgsgsacrslfggyvawemgkaedghdsmavq
iadssdwpqmkacvlvvsdikkdvsstqgmqltvatselfkeriehvvpkrfevmrkaiv
ekdfatfaketmmdsnsfhatcldsfppifymndtskriiswchtinqfygetivaytfd
agpnavlyylaenesklfafiyklfgsvpgwdkkftteqleafnhqfessnftareldle
lqkdvarviltqvgsgpqetneslidaktgl