PDB entry 1fhn
View 1fhn on RCSB PDB site
Description: transthyretin stability as a key factor in amyloidogenesis
Class: transport protein
Keywords: Amyloid, Transthyretin, Protein Stability, TRANSPORT PROTEIN
Deposited on
2000-08-02, released
2001-07-25
The last revision prior to the SCOPe 2.08 freeze date was dated
2018-08-22, with a file datestamp of
2018-08-17.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: N/A
AEROSPACI score: 0.38
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
- Uniprot P02766
- engineered mutation (118)
Domains in SCOPe 2.08: d1fhna_ - Chain 'B':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
- Uniprot P02766
- engineered mutation (118)
Domains in SCOPe 2.08: d1fhnb_ - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1fhnA (A:)
gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystma
vvtnpke
Sequence, based on observed residues (ATOM records): (download)
>1fhnA (A:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysystmavvtn
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1fhnB (B:)
gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystma
vvtnpke
Sequence, based on observed residues (ATOM records): (download)
>1fhnB (B:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysystmavvtn