PDB entry 1fea

View 1fea on RCSB PDB site
Description: unliganded crithidia fasciculata trypanothione reductase at 2.2 angstrom resolution
Class: oxidoreductase
Keywords: redox-active center, oxidoreductase, flavoprotein, fad, nadp
Deposited on 1995-07-12, released 1997-01-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.185
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: trypanothione reductase
    Species: CRITHIDIA FASCICULATA [TaxId:5656]
    Gene: TR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P39040 (0-End)
      • conflict (295)
      • conflict (477)
    Domains in SCOPe 2.08: d1feaa1, d1feaa2, d1feaa3
  • Chain 'B':
    Compound: trypanothione reductase
    Species: CRITHIDIA FASCICULATA [TaxId:5656]
    Gene: TR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P39040 (0-End)
      • conflict (295)
      • conflict (477)
    Domains in SCOPe 2.08: d1feab1, d1feab2, d1feab3
  • Chain 'C':
    Compound: trypanothione reductase
    Species: CRITHIDIA FASCICULATA [TaxId:5656]
    Gene: TR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P39040 (0-End)
      • conflict (295)
      • conflict (477)
    Domains in SCOPe 2.08: d1feac1, d1feac2, d1feac3
  • Chain 'D':
    Compound: trypanothione reductase
    Species: CRITHIDIA FASCICULATA [TaxId:5656]
    Gene: TR1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P39040 (0-End)
      • conflict (295)
      • conflict (477)
    Domains in SCOPe 2.08: d1fead1, d1fead2, d1fead3
  • Heterogens: FAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1feaA (A:)
sraydlvvigagsggleagwnaaslhkkrvavidlqkhhgpphyaalggtcvnvgcvpkk
lmvtganymdtiresagfgweldresvrpnwkaliaaknkavsgindsyegmfadteglt
fhqgfgalqdnhtvlvresadpnsavletldteyillatgswpqhlgiegddlcitsnea
fyldeapkralcvgggyisiefagifnaykarggqvdlayrgdmilrgfdselrkqlteq
lranginvrthenpakvtknadgtrhvvfesgaeadydvvmlaigrvprsqtlqlekagv
evakngaikvdaysktnvdniyaigdvtdrvmltpvainegaafvdtvfankpratdhtk
vacavfsippmgvcgyveedaakkydqvavyessftplmhnisgstykkfmvrivtnhad
gevlgvhmlgdsspeiiqsvaiclkmgakisdfyntigvhptsaeelcsmrtpayfyekg
krvekidsnl

    Sequence, based on observed residues (ATOM records): (download) 
    >1feaA (A:)
sraydlvvigagsggleagwnaaslhkkrvavidlqkhhgpphyaalggtcvnvgcvpkk
lmvtganymdtiresagfgweldresvrpnwkaliaaknkavsgindsyegmfadteglt
fhqgfgalqdnhtvlvresadpnsavletldteyillatgswpqhlgiegddlcitsnea
fyldeapkralcvgggyisiefagifnaykarggqvdlayrgdmilrgfdselrkqlteq
lranginvrthenpakvtknadgtrhvvfesgaeadydvvmlaigrvprsqtlqlekagv
evakngaikvdaysktnvdniyaigdvtdrvmltpvainegaafvdtvfankpratdhtk
vacavfsippmgvcgyveedaakkydqvavyessftplmhnisgstykkfmvrivtnhad
gevlgvhmlgdsspeiiqsvaiclkmgakisdfyntigvhptsaeelcsmrtpayfyekg
krvekid

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1feaB (B:)
sraydlvvigagsggleagwnaaslhkkrvavidlqkhhgpphyaalggtcvnvgcvpkk
lmvtganymdtiresagfgweldresvrpnwkaliaaknkavsgindsyegmfadteglt
fhqgfgalqdnhtvlvresadpnsavletldteyillatgswpqhlgiegddlcitsnea
fyldeapkralcvgggyisiefagifnaykarggqvdlayrgdmilrgfdselrkqlteq
lranginvrthenpakvtknadgtrhvvfesgaeadydvvmlaigrvprsqtlqlekagv
evakngaikvdaysktnvdniyaigdvtdrvmltpvainegaafvdtvfankpratdhtk
vacavfsippmgvcgyveedaakkydqvavyessftplmhnisgstykkfmvrivtnhad
gevlgvhmlgdsspeiiqsvaiclkmgakisdfyntigvhptsaeelcsmrtpayfyekg
krvekidsnl

    Sequence, based on observed residues (ATOM records): (download) 
    >1feaB (B:)
sraydlvvigagsggleagwnaaslhkkrvavidlqkhhgpphyaalggtcvnvgcvpkk
lmvtganymdtiresagfgweldresvrpnwkaliaaknkavsgindsyegmfadteglt
fhqgfgalqdnhtvlvresadpnsavletldteyillatgswpqhlgiegddlcitsnea
fyldeapkralcvgggyisiefagifnaykarggqvdlayrgdmilrgfdselrkqlteq
lranginvrthenpakvtknadgtrhvvfesgaeadydvvmlaigrvprsqtlqlekagv
evakngaikvdaysktnvdniyaigdvtdrvmltpvainegaafvdtvfankpratdhtk
vacavfsippmgvcgyveedaakkydqvavyessftplmhnisgstykkfmvrivtnhad
gevlgvhmlgdsspeiiqsvaiclkmgakisdfyntigvhptsaeelcsmrtpayfyekg
krve

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1feaC (C:)
sraydlvvigagsggleagwnaaslhkkrvavidlqkhhgpphyaalggtcvnvgcvpkk
lmvtganymdtiresagfgweldresvrpnwkaliaaknkavsgindsyegmfadteglt
fhqgfgalqdnhtvlvresadpnsavletldteyillatgswpqhlgiegddlcitsnea
fyldeapkralcvgggyisiefagifnaykarggqvdlayrgdmilrgfdselrkqlteq
lranginvrthenpakvtknadgtrhvvfesgaeadydvvmlaigrvprsqtlqlekagv
evakngaikvdaysktnvdniyaigdvtdrvmltpvainegaafvdtvfankpratdhtk
vacavfsippmgvcgyveedaakkydqvavyessftplmhnisgstykkfmvrivtnhad
gevlgvhmlgdsspeiiqsvaiclkmgakisdfyntigvhptsaeelcsmrtpayfyekg
krvekidsnl

    Sequence, based on observed residues (ATOM records): (download) 
    >1feaC (C:)
sraydlvvigagsggleagwnaaslhkkrvavidlqkhhgpphyaalggtcvnvgcvpkk
lmvtganymdtiresagfgweldresvrpnwkaliaaknkavsgindsyegmfadteglt
fhqgfgalqdnhtvlvresadpnsavletldteyillatgswpqhlgiegddlcitsnea
fyldeapkralcvgggyisiefagifnaykarggqvdlayrgdmilrgfdselrkqlteq
lranginvrthenpakvtknadgtrhvvfesgaeadydvvmlaigrvprsqtlqlekagv
evakngaikvdaysktnvdniyaigdvtdrvmltpvainegaafvdtvfankpratdhtk
vacavfsippmgvcgyveedaakkydqvavyessftplmhnisgstykkfmvrivtnhad
gevlgvhmlgdsspeiiqsvaiclkmgakisdfyntigvhptsaeelcsmrtpayfyekg
krvekid

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1feaD (D:)
sraydlvvigagsggleagwnaaslhkkrvavidlqkhhgpphyaalggtcvnvgcvpkk
lmvtganymdtiresagfgweldresvrpnwkaliaaknkavsgindsyegmfadteglt
fhqgfgalqdnhtvlvresadpnsavletldteyillatgswpqhlgiegddlcitsnea
fyldeapkralcvgggyisiefagifnaykarggqvdlayrgdmilrgfdselrkqlteq
lranginvrthenpakvtknadgtrhvvfesgaeadydvvmlaigrvprsqtlqlekagv
evakngaikvdaysktnvdniyaigdvtdrvmltpvainegaafvdtvfankpratdhtk
vacavfsippmgvcgyveedaakkydqvavyessftplmhnisgstykkfmvrivtnhad
gevlgvhmlgdsspeiiqsvaiclkmgakisdfyntigvhptsaeelcsmrtpayfyekg
krvekidsnl

    Sequence, based on observed residues (ATOM records): (download) 
    >1feaD (D:)
sraydlvvigagsggleagwnaaslhkkrvavidlqkhhgpphyaalggtcvnvgcvpkk
lmvtganymdtiresagfgweldresvrpnwkaliaaknkavsgindsyegmfadteglt
fhqgfgalqdnhtvlvresadpnsavletldteyillatgswpqhlgiegddlcitsnea
fyldeapkralcvgggyisiefagifnaykarggqvdlayrgdmilrgfdselrkqlteq
lranginvrthenpakvtknadgtrhvvfesgaeadydvvmlaigrvprsqtlqlekagv
evakngaikvdaysktnvdniyaigdvtdrvmltpvainegaafvdtvfankpratdhtk
vacavfsippmgvcgyveedaakkydqvavyessftplmhnisgstykkfmvrivtnhad
gevlgvhmlgdsspeiiqsvaiclkmgakisdfyntigvhptsaeelcsmrtpayfyekg
krve