PDB entry 1fcm

View 1fcm on RCSB PDB site
Description: crystal structure of the e.coli ampc beta-lactamase mutant q120l/y150e covalently acylated with the inhibitory beta-lactam, cloxacillin
Class: hydrolase/antibiotic
Keywords: beta-lactamase beta-lactam complex, enzyme inhibitor complex, hydrolase-antibiotic complex
Deposited on 2000-07-18, released 2000-12-04
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-08-24, with a file datestamp of 2011-08-19.
Experiment type: XRAY
Resolution: 2.46 Å
R-factor: 0.207
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00811 (0-357)
      • engineered (116)
      • engineered (146)
    Domains in SCOPe 2.01: d1fcma_
  • Chain 'B':
    Compound: Beta-lactamase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00811 (0-357)
      • engineered (116)
      • engineered (146)
    Domains in SCOPe 2.01: d1fcmb_
  • Heterogens: CXU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1fcmA (A:)
apqqindivhrtitplieqqkipgmavaviyqgkpyyftwgyadiakkqpvtqqtlfelg
svsktftgvlggdaiargeiklsdpttkywpeltakqwngitllhlatytagglpllvpd
evksssdllrfyqnwqpawapgtqrleanssiglfgalavkpsglsfeqamqtrvfqplk
lnhtwinvppaeeknyawgyregkavhvspgaldaeaygvkstiedmarwvqsnlkpldi
nektlqqgiqlaqsrywqtgdmyqglgwemldwpvnpdsiingsdnkialaarpvkaitp
ptpavraswvhktgatggfgsyvafipekelgivmlanknypnparvdaawqilnalq

    Sequence, based on observed residues (ATOM records): (download) 
    >1fcmA (A:)
apqqindivhrtitplieqqkipgmavaviyqgkpyyftwgyadiakkqpvtqqtlfelg
svsktftgvlggdaiargeiklsdpttkywpeltakqwngitllhlatytagglpllvpd
evksssdllrfyqnwqpawapgtqrleanssiglfgalavkpsglsfeqamqtrvfqplk
lnhtwinvppaeeknyawgyregkavhvspgaldaeaygvkstiedmarwvqsnlkpldi
nektlqqgiqlaqsrywqtgdmyqglgwemldwpvnpdsikialaarpvkaitpptpavr
aswvhktgatggfgsyvafipekelgivmlanknypnparvdaawqilnalq

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1fcmB (B:)
apqqindivhrtitplieqqkipgmavaviyqgkpyyftwgyadiakkqpvtqqtlfelg
svsktftgvlggdaiargeiklsdpttkywpeltakqwngitllhlatytagglpllvpd
evksssdllrfyqnwqpawapgtqrleanssiglfgalavkpsglsfeqamqtrvfqplk
lnhtwinvppaeeknyawgyregkavhvspgaldaeaygvkstiedmarwvqsnlkpldi
nektlqqgiqlaqsrywqtgdmyqglgwemldwpvnpdsiingsdnkialaarpvkaitp
ptpavraswvhktgatggfgsyvafipekelgivmlanknypnparvdaawqilnalq