PDB entry 1fbv
View 1fbv on RCSB PDB site
Description: structure of a cbl-ubch7 complex: ring domain function in ubiquitin-protein ligases
Class: ligase
Keywords: cbl, ubch7, ZAP-70, E2, ubiquitin, E3, phosphorylation, tyrosine kinase, ubiquitination, protein degradation,, LIGASE
Deposited on
2000-07-17, released
2000-08-30
The last revision prior to the SCOPe 2.04 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.227
AEROSPACI score: 0.22
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: signal transduction protein cbl
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d1fbva1, d1fbva2, d1fbva3, d1fbva4 - Chain 'B':
Compound: zap-70 peptide
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Chain 'C':
Compound: ubiquitin-conjugating enzyme e12-18 kda ubch7
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d1fbvc_ - Heterogens: ZN, SO4
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1fbvA (A:)
ppgtvdkkmvekcwklmdkvvrlcqnpklalknsppyildllpdtyqhlrtilsryegkm
etlgeneyfrvfmenlmkktkqtislfkegkermyeensqprrnltklslifshmlaelk
gifpsglfqgdtfritkadaaefwrkafgektivpwksfrqalhevhpissgleamalks
tidltcndyisvfefdiftrlfqpwssllrnwnslavthpgymafltydevkarlqkfih
kpgsyifrlsctrlgqwaigyvtadgnilqtiphnkplfqalidgfregfylfpdgrnqn
pdltglceptpqdhikvtqeqyelycemgstfqlckicaendkdvkiepcghlmctsclt
swqesegqgcpfcrceikgtepivvdpf
- Chain 'B':
No sequence available.
- Chain 'C':
Sequence, based on SEQRES records: (download)
>1fbvC (C:)
maasrrlmkeleeirkcgmknfrniqvdeanlltwqglivpdnppydkgafrieinfpae
ypfkppkitfktkiyhpnidekgqvclpvisaenwkpatktdqviqslialvndpqpehp
lradlaeeyskdrkkfcknaeeftkkygekrpvd
Sequence, based on observed residues (ATOM records): (download)
>1fbvC (C:)
srrlmkeleeirkcgmknfrniqvdeanlltwqglivpdnppydkgafrieinfpaeypf
kppkitfktkiyhpnidekgqvclpvisaenwkpatktdqviqslialvndpqpehplra
dlaeeyskdrkkfcknaeeftkky