PDB entry 1fbv

View 1fbv on RCSB PDB site
Description: structure of a cbl-ubch7 complex: ring domain function in ubiquitin-protein ligases
Class: ligase
Keywords: cbl, ubch7, ZAP-70, E2, ubiquitin, E3, phosphorylation, tyrosine kinase, ubiquitination, protein degradation,, LIGASE
Deposited on 2000-07-17, released 2000-08-30
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.227
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: signal transduction protein cbl
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1fbva1, d1fbva2, d1fbva3, d1fbva4
  • Chain 'B':
    Compound: zap-70 peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 1FBV (0-8)
  • Chain 'C':
    Compound: ubiquitin-conjugating enzyme e12-18 kda ubch7
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1fbvc_
  • Heterogens: ZN, SO4

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1fbvA (A:)
    ppgtvdkkmvekcwklmdkvvrlcqnpklalknsppyildllpdtyqhlrtilsryegkm
    etlgeneyfrvfmenlmkktkqtislfkegkermyeensqprrnltklslifshmlaelk
    gifpsglfqgdtfritkadaaefwrkafgektivpwksfrqalhevhpissgleamalks
    tidltcndyisvfefdiftrlfqpwssllrnwnslavthpgymafltydevkarlqkfih
    kpgsyifrlsctrlgqwaigyvtadgnilqtiphnkplfqalidgfregfylfpdgrnqn
    pdltglceptpqdhikvtqeqyelycemgstfqlckicaendkdvkiepcghlmctsclt
    swqesegqgcpfcrceikgtepivvdpf
    

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >1fbvC (C:)
    maasrrlmkeleeirkcgmknfrniqvdeanlltwqglivpdnppydkgafrieinfpae
    ypfkppkitfktkiyhpnidekgqvclpvisaenwkpatktdqviqslialvndpqpehp
    lradlaeeyskdrkkfcknaeeftkkygekrpvd
    

    Sequence, based on observed residues (ATOM records): (download)
    >1fbvC (C:)
    srrlmkeleeirkcgmknfrniqvdeanlltwqglivpdnppydkgafrieinfpaeypf
    kppkitfktkiyhpnidekgqvclpvisaenwkpatktdqviqslialvndpqpehplra
    dlaeeyskdrkkfcknaeeftkky