PDB entry 1fb7
View 1fb7 on RCSB PDB site
Description: crystal structure of an in vivo hiv-1 protease mutant in complex with saquinavir: insights into the mechanisms of drug resistance
Class: hydrolase/hydrolase inhibitor
Keywords: HIV protease, mutant, drug resistance, Viral protein, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
Deposited on
2000-07-14, released
2000-12-13
The last revision prior to the SCOPe 2.04 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-08.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.187
AEROSPACI score: 0.32
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: hiv-1 protease
Species: Human immunodeficiency virus 1 [TaxId:11676]
Database cross-references and differences (RAF-indexed):
- Uniprot Q72874 (0-98)
- engineered (47)
- engineered (89)
Domains in SCOPe 2.04: d1fb7a_ - Heterogens: ROC, HOH