PDB entry 1f5a

View 1f5a on RCSB PDB site
Description: crystal structure of mammalian poly(a) polymerase
Class: transferase
Keywords: mRNA processing, transferase, transcription, RNA-binding, phosphorylation, nuclear protein, alternative splicing helical turn motif, nucleotidyl transferase catalytic domain
Deposited on 2000-06-13, released 2000-09-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.219
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: poly(a) polymerase
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P25500
      • modified (250)
      • modified (312)
      • modified (334)
      • modified (336)
      • modified (435)
      • modified (475)
      • modified (480)
      • modified (485)
    Domains in SCOPe 2.08: d1f5aa1, d1f5aa3, d1f5aa4
  • Heterogens: MN, 3AT, 3PO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1f5aA (A:)
mpfpvttqgsqqtqppqkhygitspislaapketdclltqklvetlkpfgvfeeeeelqr
rililgklnnlvkewireisesknlpqsvienvggkiftfgsyrlgvhtkgadidalcva
prhvdrsdfftsfydklklqeevkdlraveeafvpviklcfdgieidilfarlalqtipe
dldlrddsllknldircirslngcrvtdeilhlvpnidnfrltlraiklwakrhniysni
lgflggvswamlvartcqlypnaiastlvhkfflvfskwewpnpvllkqpeecnlnlpvw
dprvnpsdryhlmpiitpaypqqnstynvsvstrmvmveefkqglaitdeillskaewsk
lfeapnffqkykhyivllasaptekqrlewvglveskirilvgsleknefitlahvnpqs
fpapkenpdkeefrtmwviglvfkktensenlsvdltydiqsftdtvyrqainskmfevd
mkiaamhvkrkqlhqllpshvlqkkkkhstegv

    Sequence, based on observed residues (ATOM records): (download) 
    >1f5aA (A:)
ygitspislaapketdclltqklvetlkpfgvfeeeeelqrrililgklnnlvkewirei
sesknlpqsvienvggkiftfgsyrlgvhtkgadidalcvaprhvdrsdfftsfydklkl
qeevkdlraveeafvpviklcfdgieidilfarlalqtipedldlrddsllknldircir
slngcrvtdeilhlvpnidnfrltlraiklwakrhniysnilgflggvswamlvartcql
ypnaiastlvhkfflvfskwewpnpvllkqpeecnlnlpvwdprvnpsdryhlmpiitpa
ypqqnstynvsvstrmvmveefkqglaitdeillskaewsklfeapnffqkykhyivlla
saptekqrlewvglveskirilvgsleknefitlahvnpqsfpakeefrtmwviglvfkd
ltydiqsftdtvyrqainskmfevdmkiaamhvkrkqlhqllp