PDB entry 1f28

View 1f28 on RCSB PDB site
Description: crystal structure of thymidylate synthase from pneumocystis carinii bound to dump and bw1843u89
Class: transferase
Keywords: beta-sheet, protein-inhibitor complex, TRANSFERASE
Deposited on 2000-05-23, released 2001-06-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-31, with a file datestamp of 2018-01-26.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidylate synthase
    Species: Pneumocystis carinii [TaxId:4754]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1f28a_
  • Chain 'B':
    Compound: Thymidylate synthase
    Species: Pneumocystis carinii [TaxId:4754]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1f28b_
  • Chain 'C':
    Compound: Thymidylate synthase
    Species: Pneumocystis carinii [TaxId:4754]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1f28c_
  • Chain 'D':
    Compound: Thymidylate synthase
    Species: Pneumocystis carinii [TaxId:4754]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1f28d_
  • Heterogens: UMP, F89, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1f28A (A:)
mvnaeeqqylnlvqyiinhgedrpdrtgtgtlsvfapsplkfslrnktfpllttkrvfir
gvieellwfirgetdslklreknihiwdangsreyldsigltkrqegdlgpiygfqwrhf
gaeyidcktnyigqgvdqlaniiqkirtspydrrlilsawnpadlekmalppchmfcqfy
vhipsnnhrpelscqlyqrscdmglgvpfniasyalltcmiahvcdldpgdfihvmgdch
iykdhiealqqqltrsprpfptlslnrsitdiedftlddfniqnyhpyetikmkmsi

    Sequence, based on observed residues (ATOM records): (download) 
    >1f28A (A:)
naeeqqylnlvqyiinhgedrpdrtgtgtlsvfapsplkfslrnktfpllttkrvfirgv
ieellwfirgetdslklreknihiwdangsreyldsigltkrqegdlgpiygfqwrhfga
eyidcktnyigqgvdqlaniiqkirtspydrrlilsawnpadlekmalppchmfcqfyvh
ipsnnhrpelscqlyqrscdmglgvpfniasyalltcmiahvcdldpgdfihvmgdchiy
kdhiealqqqltrsprpfptlslnrsitdiedftlddfniqnyhpyetikmkmsi

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1f28B (B:)
mvnaeeqqylnlvqyiinhgedrpdrtgtgtlsvfapsplkfslrnktfpllttkrvfir
gvieellwfirgetdslklreknihiwdangsreyldsigltkrqegdlgpiygfqwrhf
gaeyidcktnyigqgvdqlaniiqkirtspydrrlilsawnpadlekmalppchmfcqfy
vhipsnnhrpelscqlyqrscdmglgvpfniasyalltcmiahvcdldpgdfihvmgdch
iykdhiealqqqltrsprpfptlslnrsitdiedftlddfniqnyhpyetikmkmsi

    Sequence, based on observed residues (ATOM records): (download) 
    >1f28B (B:)
naeeqqylnlvqyiinhgedrpdrtgtgtlsvfapsplkfslrnktfpllttkrvfirgv
ieellwfirgetdslklreknihiwdangsreyldsigltkrqegdlgpiygfqwrhfga
eyidcktnyigqgvdqlaniiqkirtspydrrlilsawnpadlekmalppchmfcqfyvh
ipsnnhrpelscqlyqrscdmglgvpfniasyalltcmiahvcdldpgdfihvmgdchiy
kdhiealqqqltrsprpfptlslnrsitdiedftlddfniqnyhpyetikmkmsi

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1f28C (C:)
mvnaeeqqylnlvqyiinhgedrpdrtgtgtlsvfapsplkfslrnktfpllttkrvfir
gvieellwfirgetdslklreknihiwdangsreyldsigltkrqegdlgpiygfqwrhf
gaeyidcktnyigqgvdqlaniiqkirtspydrrlilsawnpadlekmalppchmfcqfy
vhipsnnhrpelscqlyqrscdmglgvpfniasyalltcmiahvcdldpgdfihvmgdch
iykdhiealqqqltrsprpfptlslnrsitdiedftlddfniqnyhpyetikmkmsi

    Sequence, based on observed residues (ATOM records): (download) 
    >1f28C (C:)
naeeqqylnlvqyiinhgedrpdrtgtgtlsvfapsplkfslrnktfpllttkrvfirgv
ieellwfirgetdslklreknihiwdangsreyldsigltkrqegdlgpiygfqwrhfga
eyidcktnyigqgvdqlaniiqkirtspydrrlilsawnpadlekmalppchmfcqfyvh
ipsnnhrpelscqlyqrscdmglgvpfniasyalltcmiahvcdldpgdfihvmgdchiy
kdhiealqqqltrsprpfptlslnrsitdiedftlddfniqnyhpyetikmkmsi

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1f28D (D:)
mvnaeeqqylnlvqyiinhgedrpdrtgtgtlsvfapsplkfslrnktfpllttkrvfir
gvieellwfirgetdslklreknihiwdangsreyldsigltkrqegdlgpiygfqwrhf
gaeyidcktnyigqgvdqlaniiqkirtspydrrlilsawnpadlekmalppchmfcqfy
vhipsnnhrpelscqlyqrscdmglgvpfniasyalltcmiahvcdldpgdfihvmgdch
iykdhiealqqqltrsprpfptlslnrsitdiedftlddfniqnyhpyetikmkmsi

    Sequence, based on observed residues (ATOM records): (download) 
    >1f28D (D:)
naeeqqylnlvqyiinhgedrpdrtgtgtlsvfapsplkfslrnktfpllttkrvfirgv
ieellwfirgetdslklreknihiwdangsreyldsigltkrqegdlgpiygfqwrhfga
eyidcktnyigqgvdqlaniiqkirtspydrrlilsawnpadlekmalppchmfcqfyvh
ipsnnhrpelscqlyqrscdmglgvpfniasyalltcmiahvcdldpgdfihvmgdchiy
kdhiealqqqltrsprpfptlslnrsitdiedftlddfniqnyhpyetikmkmsi