PDB entry 1ezx
View 1ezx on RCSB PDB site
Description: crystal structure of a serpin:protease complex
Class: hydrolase/hydrolase inhibitor
Keywords: protease-inhibitor complex, serpin, alpha-1-antitrypsin, trypsin, HYDROLASE/HYDROLASE INHIBITOR COMPLEX
Deposited on
2000-05-12, released
2000-10-25
The last revision prior to the SCOPe 2.03 freeze date was dated
2009-02-24, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.205
AEROSPACI score: 0.3
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: alpha-1-antitrypsin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d1ezx.1 - Chain 'B':
Compound: alpha-1-antitrypsin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d1ezx.1 - Chain 'C':
Compound: Trypsin
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d1ezxc_ - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1ezxA (A:)
nkitpnlaefafslyrqlahqsnstniffspvsiatafamlslgtkadthdeileglnfn
lteipeaqihegfqellrtlnqpdsqlqlttgnglflseglklvdkfledvkklyhseaf
tvnfgdteeakkqindyvekgtqgkivdlvkeldrdtvfalvnyiffkgkwerpfevkdt
eeedfhvdqvttvkvpmmkrlgmfniqhckklsswvllmkylgnataifflpdegklqhl
enelthdiitkflenedrrsaslhlpklsitgtydlksvlgqlgitkvfsngadlsgvte
eaplklskavhkavltidekgteaagamfleaipm
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>1ezxB (B:)
sippevkfnkpfvflmieqntksplfmgkvvnptqk
- Chain 'C':
Sequence, based on SEQRES records: (download)
>1ezxC (C:)
fiflallgaavafpvddddkivggytcgantvpyqvslnsgyhfcggslinsqwvvsaah
cyksgiqvrlgedninvvegneqfisasksivhpsynsntlnndimliklksaaslnsrv
asislptscasagtqclisgwgntkssgtsypdvlkclkapilsdsscksaypgqitsnm
fcagyleggkdscqgdsggpvvcsgklqgivswgsgcaqknkpgvytkvcnyvswikqti
asn
Sequence, based on observed residues (ATOM records): (download)
>1ezxC (C:)
cggslinsqwvvsaahcyksasksivhpsynsntlnndimliklkislptscasagtqcl
iclkapilsdsscksaypgqitsnmfcagylcqgdsggpvvcsgklqgivswgsgcaqkp
gvytkvcnyvswikqtiasn