PDB entry 1ezu

View 1ezu on RCSB PDB site
Description: ecotin y69f, d70p bound to d102n trypsin
Class: hydrolase/inhibitor
Keywords: macromolecular complex, protease inhibitor, protein-protein interactions, HYDROLASE/INHIBITOR COMPLEX
Deposited on 2000-05-11, released 2000-06-23
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.218
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ecotin
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23827
      • engineered (68-69)
    Domains in SCOPe 2.06: d1ezua_
  • Chain 'B':
    Compound: ecotin
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23827 (Start-141)
      • engineered (68-69)
    Domains in SCOPe 2.06: d1ezub_
  • Chain 'C':
    Compound: trypsin II, anionic
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00763
      • see remark 999 (60)
      • engineered (83)
    Domains in SCOPe 2.06: d1ezuc_
  • Chain 'D':
    Compound: trypsin II, anionic
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00763 (0-222)
      • see remark 999 (60)
      • engineered (83)
    Domains in SCOPe 2.06: d1ezud_
  • Heterogens: CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1ezuA (A:)
aesvqplekiapypqaekgmkrqviqltpqedestlkvelligqtlevdcnlhrlggkle
nktlegwgfpyyvfdkvsspvstmmacpdgkkekkfvtaylgdagmlrynsklpivvytp
dnvdvkyrvwkaeekidnavvr

    Sequence, based on observed residues (ATOM records): (download) 
    >1ezuA (A:)
svqplekiapypqaekgmkrqviqltpqedestlkvelligqtlevdcnlhrlggklenk
tlegwgfpyyvfdkvsspvstmmacpdgkkekkfvtaylgdagmlrynsklpivvytpdn
vdvkyrvwkaeekidnavvr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1ezuB (B:)
aesvqplekiapypqaekgmkrqviqltpqedestlkvelligqtlevdcnlhrlggkle
nktlegwgfpyyvfdkvsspvstmmacpdgkkekkfvtaylgdagmlrynsklpivvytp
dnvdvkyrvwkaeekidnavvr

    Sequence, based on observed residues (ATOM records): (download) 
    >1ezuB (B:)
svqplekiapypqaekgmkrqviqltpqedestlkvelligqtlevdcnlhrlggklenk
tlegwgfpyyvfdkvsspvstmmacpdgkkekkfvtaylgdagmlrynsklpivvytpdn
vdvkyrvwkaeekidnavvr

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1ezuC (C:)
ivggytcqensvpyqvslnsgyhfcggslindqwvvsaahcyksriqvrlgehninvleg
deqfvnaakiikhpnfdrktlnnnimliklsspvklnarvatvalpsscapagtqclisg
wgntlssgvnepdllqcldapllpqadceasypgkitdnmvcvgfleggkdscqgdsggp
vvcngelqgivswgygcalpdnpgvytkvcnyvdwiqdtiaan

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1ezuD (D:)
ivggytcqensvpyqvslnsgyhfcggslindqwvvsaahcyksriqvrlgehninvleg
deqfvnaakiikhpnfdrktlnnnimliklsspvklnarvatvalpsscapagtqclisg
wgntlssgvnepdllqcldapllpqadceasypgkitdnmvcvgfleggkdscqgdsggp
vvcngelqgivswgygcalpdnpgvytkvcnyvdwiqdtiaan